Search
Menu
Cognex Corp. - Smart Sensor 3-24 GIF LB

Making Fluorescence Correlation Spectroscopy Flexible

Facebook X LinkedIn Email
Gary Boas

Fluorescence correlation spectroscopy helps to shed light on the behavior of molecules in aqueous solutions by measuring fluctuations in fluorescence intensity. Typically, data is collected from a single, fixed-focus position within the sample. However, many applications — monitoring of large-scale translocation and spatial dynamics, for instance — require multiple excitation and detection schemes. Scientists have evaluated electron multiplying CCD (EMCCD) cameras for detection in fluorescence correlation spectroscopy, comparing their performance with that of conventional avalanche...Read full article

Related content from Photonics Media



    Articles


    Products


    Photonics Handbook Articles


    White Papers


    Webinars


    Photonics Dictionary Terms


    Media


    Photonics Buyers' Guide Categories


    Companies
    Published: September 2006
    Glossary
    fluorescence correlation spectroscopy
    A powerful method, referred to as FCS, for determining the average diffusion coefficients of fluorescent molecules in solution or membranes. FCS measurements rely on recording the transition of several thousands of molecules through the focal volume. The combination of short measurement times along with free positioning or scanning of the observation spot makes FCS an excellent tool for investigating diffusion heterogeneity over time and space.
    Featuresfluorescence correlation spectroscopyfluorescence intensityMicroscopySensors & Detectorsspatial dynamics

    We use cookies to improve user experience and analyze our website traffic as stated in our Privacy Policy. By using this website, you agree to the use of cookies unless you have disabled them.