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Metal Labels Produce 3D Images of Neurons

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Spectral confocal microscopy has been used to visualize neurons with the help of silver- and gold-based cell labeling. The development enables imaging of archived tissue samples, which could aid long-term clinical research efforts and diagnostics for cancer and neurological disorders. The staining of neurons with silver began in the 1800s, and now researchers from the University of Minnesota and Agnes Scott College in Decatur, Ga., have coupled the technique with spectral confocal microscopy, which has typically been used for fluorescence imaging. Silver-impregnated dendrites from...Read full article

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