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NIH Team Improves 3D Imaging Efficiency, Speed and Resolution

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Scientists have developed a technique that improves the spatiotemporal resolution and collection efficiency of light-sheet fluorescence microscopy (LSFM), without modifying the underlying microscope. The technique instead uses reflection to improve speed, resolution and light efficiency. A reflective, mirrored coverslip is used in place of a conventional glass coverslip. Computational imaging algorithms are used to remove unwanted background from the image and process the resulting data. Researchers at the National Institute of Biomedical Imaging and Bioengineering High Resolution...Read full article

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