Cerebral near-infrared spectroscopy oximeters can alert physicians to premature infants’ exposure to hypoxia. As European researchers push to make this technology a standard clinical tool in neonatal intensive care units, an optoacoustic alternative is emerging.JAMES SCHLETT, EDITOR, [email protected]In 1985, a team of researchers at Duke University Medical Center in Durham, N.C., pointed out the incongruity that, while the goal of intensive care for preterm newborns is to ensure their brains were receiving sufficient oxygen, neonatal intensive care units (NICUs) lacked a direct, noninvasive way to measure cerebral oxygenation. Instead, NICU staff had to rely on indirect methods, such as monitoring blood-oxygen content and transcutaneous oxygen at sites far from the brain, usually the chest or foot. 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