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Optical Coherence Tomography Aids Cancer Detection

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OCT identifies diagnostic markers in esophageal malignancies.

Florian Bazant-Hegemark and Dr. Nick Stone, Gloucestershire Royal Hospital, and Dr. Gordon McKenzie and Jon Holmes, Michelson Diagnostics Ltd.

Optical coherence tomography (OCT) has been applied successfully in ophthalmology since the early 1990s, a success story triggering research efforts in the imaging of early epithelial cancers. Typical nonophthalmic systems achieve a resolution of 10 to 20 μm in dense tissue, but imaging depth is limited to little more than 1 mm. Furthermore, early systems did not provide sufficient image contrast or penetration depth, and they scanned too slowly to combat motion blur when used in vivo. However, advances in the underlying technology (particularly light sources) have led to...Read full article

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    Published: November 2007
    Glossary
    ophthalmology
    Ophthalmology is a branch of medicine that focuses on the anatomy, physiology, and diseases of the eyes and visual system. Ophthalmologists are medical doctors who specialize in the diagnosis, treatment, and prevention of eye disorders and diseases. They are trained to provide comprehensive eye care, including medical, surgical, and optical interventions. Key areas within ophthalmology include: General eye care: Ophthalmologists perform routine eye examinations to assess visual acuity,...
    optical coherence tomography
    Optical coherence tomography (OCT) is a non-invasive imaging technique used in medical and scientific fields to capture high-resolution, cross-sectional images of biological tissues. It provides detailed, real-time, and three-dimensional visualization of tissue structures at the micrometer scale. OCT is particularly valuable in ophthalmology, cardiology, dermatology, and various other medical specialties. Here are the key features and components of optical coherence tomography: Principle of...
    BiophotonicsFeaturesMicroscopynonophthalmic systemophthalmologyoptical coherence tomography

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