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Optics Peers Through the Haze of Dementia

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Imaging of the eyes is providing a window into the brain deterioration of those with Alzheimer’s disease, promising early diagnosis and potentially benefiting both patients and researchers.

DOUGLAS FARMER, SENIOR EDITOR [email protected]

As the number of people suffering from Alzheimer’s disease (AD) and related dementias grows, so too does the pressure on the medical community to identify dementias as early as possible and potentially treat them. Researchers on both sides of the Atlantic are using optical technologies to capture the manifestations of dementia in the brain before outward symptoms of the condition occur. Optics may hold the key to unlocking the mysteries of memory loss and AD. And as it turns out, those with an eye toward early AD diagnosis may just have found the answer in the eyes of people...Read full article

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    Published: September 2019
    Glossary
    raman spectroscopy
    Raman spectroscopy is a technique used in analytical chemistry and physics to study vibrational, rotational, and other low-frequency modes in a system. Named after the Indian physicist Sir C.V. Raman who discovered the phenomenon in 1928, Raman spectroscopy provides information about molecular vibrations by measuring the inelastic scattering of monochromatic light. Here is a breakdown of the process: Incident light: A monochromatic (single wavelength) light, usually from a laser, is...
    Alzheimers diseasemultimodal retinal imagingOCToctaultrawide-fieldFuchs' dystrophygeographic atrophymacular degenerationMOON projectmolecular biomarkersRaman spectroscopyNA-ADNINIHNIBIBSFDILEDsneuroscienceFeatures

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