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Optochemogenetics Tested for Neuronal Repair after Stroke

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Researchers at Emory University School of Medicine have developed optochemogenetics, a combinatorial approach based on optogenetics and chemogenetics, to enable the selective, noninvasive stimulation of brain cells using light. In a mouse model of stroke, neural progenitor cells that received light stimulation through optochemogenetics promoted functional recovery in the mice. The Emory investigators wanted to remove the fiber optic cable that optogenetics approaches use to activate or inhibit neurons. The researchers created luminopsins — engineered proteins that are both...Read full article

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