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Optogenetic Method Erases, Reactivates Memories

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A new light-based technique could essentially control memories, showing potential for treating brain-related conditions such as Alzheimer’s disease. A team from the University of California, San Diego, has discovered how to use optogenetics to deactivate and then reactivate memories in the brains of genetically engineered rats. This is the first evidence demonstrating that this can be done by stimulating nerves in the brain via synapsis. “We can form a memory, erase that memory, and we can reactivate it at will by applying a stimulus that selectively strengthens or...Read full article

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    Published: June 2014
    Glossary
    optogenetics
    A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light. Only the cells that have been modified to include light-sensitive proteins will be under control of the light. The ability to selectively target cells gives researchers precise control. Using light to control the excitation, inhibition and signaling pathways of specific cells or groups of...
    Alzheimers diseaseAmericasBiophotonicsBioScanbrainCaliforniaLTPoptical pulsesOpticsoptogeneticsResearch & TechnologysynapsisTest & MeasurementUniversity of California San DiegoDr. Roberto Malinowlong-term potentiationSadegh Nabavi

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