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Optogenetics: A Conversation with Ed Boyden

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Gary Boas, News Editor, [email protected]

In a few short years, optogenetics has gone from a glimmer in the eye in a handful of researchers to a viable technique used worldwide to study information processing in the brain. We recently caught up with one of the originators of the technique and talked about his role in its development while also exploring future avenues of research. Ed Boyden is a well-known figure in the field of optogenetics: a pioneer of the technology and, in 2008, one of Discover Magazine’s top 20 scientists under 40. Now head of the Synthetic Neurobiology Group at MIT in Cambridge, he traces his role in...Read full article

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    Published: October 2010
    Glossary
    optical fiber
    Optical fiber is a thin, flexible, transparent strand or filament made of glass or plastic used for transmitting light signals over long distances with minimal loss of signal quality. It serves as a medium for conveying information in the form of light pulses, typically in the realm of telecommunications, networking, and data transmission. The core of an optical fiber is the central region through which light travels. It is surrounded by a cladding layer that has a lower refractive index than...
    optical switching
    Optical switching refers to the process of controlling the routing or transmission of optical signals within a network using various techniques to selectively switch or redirect optical paths. This is essential in optical communication systems, where data is transmitted as light signals over optical fibers. Optical switching technologies enable efficient, high-speed, and flexible routing of optical signals, enhancing the performance and scalability of optical networks. There are several types...
    optogenetics
    A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light. Only the cells that have been modified to include light-sensitive proteins will be under control of the light. The ability to selectively target cells gives researchers precise control. Using light to control the excitation, inhibition and signaling pathways of specific cells or groups of...
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