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Optogenetics Device Offers Stable Way to Treat Bladder Problems

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A tiny, implantable device has been introduced that can detect overactivity in the bladder and use light from biointegrated LEDs to tamp down the urge to urinate. The device has been demonstrated in laboratory rats and could one day be used to treat overactive bladder, urinary incontinence, and interstitial cystitis in people. It was created by a team of neuroscientists and engineers at the Washington University School of Medicine, the University of Illinois at Urbana-Champaign, and the Feinberg School of Medicine at Northwestern University. The researchers implanted a soft, stretchy...Read full article

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    BioPhotonics
    Apr 2019
    GLOSSARY
    optoelectronics
    A sub-field of photonics that pertains to an electronic device that responds to optical power, emits or modifies optical radiation, or utilizes optical radiation for its internal operation. Any device that functions as an electrical-to-optical or optical-to-electrical transducer. Electro-optic often is used erroneously as a synonym.
    optogenetics
    A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light. Only the cells that have been modified to include light-sensitive proteins will be under control of the light. The ability to selectively target cells gives researchers precise control. Using light to control the excitation, inhibition and signaling pathways of specific cells or groups of...
    photobiomodulation
    A light therapy that utilizes nonionizing light sources, including lasers, LEDs, and broadband light, in the visible and infrared spectrum. It is a nonthermal process involving endogenous chromophores eliciting photophysical (i.e., linear and nonlinear) and photochemical events at various biological scales. This process results in beneficial therapeutic outcomes, including but not limited to the alleviation of pain or inflammation, immunomodulation, and promotion of wound healing and tissue...
    Research & TechnologyeducationAmericasWashington UniversityLEDslight sourcesopticsoptoelectronicsSensors & Detectorsmedicinemedicallight therapyoptogeneticsphotobiomodulationBiophotonicsbioengineeringbladder controloveractive bladderBioScan

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