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Optogenetics Drives Structural Changes in Embryo Tissue Development

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Scientists at the European Molecular Biology Laboratory (EMBL) used optogenetics to drive structural changes in tissue development in Drosophila (fruit fly) embryos. Their experimental results showed that optogenetics can be used to inhibit the naturally occurring process of invagination. To form internal organs, groups of cells must move toward the inside of an embryo. During this process, called invagination, the surface of the cell grouping contracts and causes tissue to fold inward. The cell grouping initiates the force needed to cause the tissue invagination. Abnormalities in this...Read full article

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