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Plasmonic Probes Help Quantify Breast Cancer Gene Segments

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Hyperspectral imaging using plasmonic probes can ferret out a specific genetic telltale for breast cancer within individual cells, according to recent research from Purdue University. That genetic telltale is BRCA1, a tumor suppressor gene. Measuring the number of BRCA1 messenger RNA (mRNA) splice variants in a cell can indicate if the gene is being under-expressed, a possible sign of breast cancer. Existing methods for detecting BRCA1 rely on samples made up of hundreds or thousands of cells, and cannot provide detailed information about how genes tied to cancer are being expressed. ...Read full article

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    Published: April 2014
    Glossary
    hyperspectral imaging
    Hyperspectral imaging is an advanced imaging technique that captures and processes information from across the electromagnetic spectrum. Unlike traditional imaging systems that record only a few spectral bands (such as red, green, and blue in visible light), hyperspectral imaging collects data in numerous contiguous bands, covering a wide range of wavelengths. This extended spectral coverage enables detailed analysis and characterization of materials based on their spectral signatures. Key...
    nano
    An SI prefix meaning one billionth (10-9). Nano can also be used to indicate the study of atoms, molecules and other structures and particles on the nanometer scale. Nano-optics (also referred to as nanophotonics), for example, is the study of how light and light-matter interactions behave on the nanometer scale. See nanophotonics.
    AmericasBindley Bioscience CenterBiophotonicsBioScanBRCA1breast cancerhyperspectral imagingImagingMaterialsnanoNature NanotechnologyPurdue UniversityResearch & Technologyspectroscopymessenger RNAplasmonic couplingJoseph Irudayaraj

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