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Pulsed Lasers Pierce the Diffraction Limit in Medicine

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A research project aims to realize deeper optical imaging techniques for cancer diagnosis and monitoring of the human body.

REGINA GUMENYUK, TAMPERE UNIVERSITY; PABLO LOZA-ALVAREZ, THE INSTITUTE OF PHOTONIC SCIENCES (ICFO); AND SIMONE MORSELLI, UNIVERSITY OF FLORENCE

Optical imaging of tissues in diagnostics is a burgeoning field of research, and related technology has shown the ability to provide rapid, sensitive, and specific data that discriminates disease-related characteristics. However, the depth at which high-quality imaging can be performed in tissue by existing systems has historically been limited to only a few hundred microns. This hinders examination and detection of deeper disease markers or morphologies. Recent results in multiphoton imaging suggest that three-photon imaging with excitation at a wavelength of 1700 nm has a penetration...Read full article

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