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Quantum Dots Replace Dyes to Stabilize Cell Imaging

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A new molecular probe, based on the fluorescence in situ hybridization (FISH) technique, uses compact quantum dots (QDs) instead of fluorescent dyes to illuminate molecules and diseased cells. Developed by a team from the University of Illinois at Urbana-Champaign and the Mayo Clinic, the QDs provide greater stability and accuracy compared with dyes. Quantum dots illuminate the locations of individual mRNA as red dots in the cytoplasm of a single HeLa cell. The blue region is the nucleus. This work was a collaborative effort between Illinois Bioengineering and Mayo Clinic researchers....Read full article

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