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Resolution of Optical Microscope Redefined

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Digital imaging requires a re-examination of the resolution limits of optical microscopy.

Sripad Ram, Dr. E. Sally Ward and Dr. Raimund J. Ober

Optical microscopy is an important tool for studying live biological cells in life sciences research, enabling the observation of various biological processes in real time. The study of nanoscale single molecular activities such as protein-protein interactions is vital for understanding cellular processes and aids in the development of new drugs. Recent advances in imaging technology and labeling methodology have enabled the study of single biomolecules even within a cellular environment. It is widely believed that optical microscopes have a finite resolution limit given by...Read full article

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