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Seeing Cells Through Silicon

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ARLINGTON, Texas, & CAMBRIDGE, Mass., Oct. 4, 2013 — A new type of near-infrared microscopy can image cells through a silicon wafer, providing more information about diseased or infected cells flowing through microfluidic devices. “This has the potential to merge research in cellular visualization with all the exciting things you can do on a silicon wafer,” said Ishan Barman, a former postdoc in MIT’s Laser Biomedical Research Center (LBRC) and a lead author of a paper on the technology. Silicon, the workhorse of the microelectronics industry, is commonly used to build lab-on a-chip microfluidic devices, which can...Read full article

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    Published: October 2013
    Glossary
    nano
    An SI prefix meaning one billionth (10-9). Nano can also be used to indicate the study of atoms, molecules and other structures and particles on the nanometer scale. Nano-optics (also referred to as nanophotonics), for example, is the study of how light and light-matter interactions behave on the nanometer scale. See nanophotonics.
    quantitative phase imaging
    Quantitative phase imaging (QPI) is an advanced imaging technique used in microscopy to measure and analyze the optical phase information of transparent specimens. Unlike traditional brightfield microscopy, which relies on the absorption of light, QPI directly captures and quantifies the phase changes induced by a specimen as light passes through it. This enables the visualization of transparent structures and provides valuable quantitative information about biological and non-biological...
    CMOSAmericasbioengineeringbiomedical imagingBiophotonicscell imagingcell imaging through siliconhelium neon laserImagingIshan Barmanlab on a chipLasersMaterials & ChemicalsmicrofluidicMicroscopyMITnanoNanoscope TechnologiesNarahara Chari DingariNational Institute of Biomedical Imaging and Bioengineeringquantitative phase imagingResearch & TechnologySamarendra MohantyTi:sapphire laserUTA

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