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Simultaneous cancer imaging and therapy

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In a review of nanoparticles for cancer therapy and imaging, the authors describe the challenges and future of the technology. A major dilemma is how to design nanoparticles that travel to the tumor and kill it without harming healthy tissue. The solution can be summarized in one word: targeting. Targeting usually exploits tumor biology, and active targeting usually requires conjugation of a ligand to a drug, such as one that recognizes a tumor marker. On the other hand, passive targeting typically does not require conjugation of a ligand to a drug. For example, nanoparticles can be made...Read full article

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    Published: August 2007
    BiophotonicsFrom The JournalsImagingnanoparticlesResearch & Technology

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