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Spectroscopic ‘Fingerprints’ Diagnose Brain Tumors

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LANCASTER, England, Sept. 21, 2012 — A breakthrough in brain tumor diagnosis uses infrared and Raman spectroscopy to differentiate healthy from diseased tissue based on individual biochemical-cell “fingerprints.” Currently, it is difficult for surgeons to determine where the tumor ends and normal tissue begins. But now research from Lancaster University has shown that Raman spectroscopy, a method that works effectively on living tissue, makes it possible to spot the difference between cancer and normal tissue, yielding accurate results in seconds. The new technique, which is coupled with statistical...Read full article

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    Sep 2012
    Immunohistochemistry (IHC) is a method for detecting antigens or haptens in cells of a tissue section by using labeled antibodies to bind specifically to their antigens. IHC is used for disease diagnosis, biological research and in drug development. Using IHC visualized tumor markers such as enzymes, oncogenes and tumor-specific antigens, physicians can diagnose if a tumor is benign or malignant and determine the stage and grade of a cancer.
    infrared spectroscopy
    The measurement of the ability of matter to absorb, transmit or reflect infrared radiation and the relating of the resultant data to chemical structure.
    The technology of generating and harnessing light and other forms of radiant energy whose quantum unit is the photon. The science includes light emission, transmission, deflection, amplification and detection by optical components and instruments, lasers and other light sources, fiber optics, electro-optical instrumentation, related hardware and electronics, and sophisticated systems. The range of applications of photonics extends from energy generation to detection to communications and...
    raman spectroscopy
    That branch of spectroscopy concerned with Raman spectra and used to provide a means of studying pure rotational, pure vibrational and rotation-vibration energy changes in the ground level of molecules. Raman spectroscopy is dependent on the collision of incident light quanta with the molecule, inducing the molecule to undergo the change.
    1. A generic term for detector. 2. A complete optical/mechanical/electronic system that contains some form of radiation detector.
    Basic Sciencebiochemical-cell fingerprintBiophotonicsbrain cancerbrain tumor diagnosisbrain tumorsdiseased tissue distinctionEnglandEuropeFrancis Martinhealthy tissue distinctionimagingimmunohistochemistryinfrared spectroscopyLancaster Universityliving tissuephotonicsradiation therapyRaman spectroscopyResearch & TechnologysensorSensors & Detectorsspectroscopy

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