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Spectroscopic Methods Guide Precision Medicine

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Combining Raman techniques with chip-based sampling enables the identification of cells and bacteria and can also provide information on antibiotic resistance.

Susanne Pahlow, Karina Weber, and Jürgen Popp, Leibniz Institute of Photonic Technology

Raman spectroscopy captures the effect when light partially scatters inelastically as it interacts with matter. The amounts of energy transferred between photons and molecules during this process correspond to specific molecular vibrations. Therefore, Raman spectroscopy is ideally suited for characterizing and identifying the chemical composition of various samples because the spectra provide a “molecular fingerprint.” When highly complex samples such as microorganisms, cells, and tissue are investigated, all Raman active components — such as proteins, nucleic acids,...Read full article

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