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Spectroscopy Guides Precision Medicine

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Combining Raman techniques with chip-based sampling enables the identification of cells and bacteria and can also provide information on antibiotic resistance.

Susanne Pahlow, Karina Weber, and Jürgen Popp, Leibniz Institute of Photonic Technology

Raman spectroscopy captures the effect when light partially scatters inelastically as it interacts with matter. The amounts of energy transferred between photons and molecules during this process correspond to specific molecular vibrations. Therefore, Raman spectroscopy is ideally suited for characterizing and identifying the chemical composition of various samples because the spectra provide a molecular “fingerprint.” Antibodies attack a virus pathogen cell. Courtesy of iStock.com/Christoph Burgstedt. When highly complex samples such as microorganisms, cells, and...Read full article

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