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Superresolution Microscopy Images Common Alzheimer’s Protein

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DOUGLAS FARMER, SENIOR EDITOR
[email protected]

As superresolution microscopy has advanced, so too has scientists’ ability to dive deep into the neural network and the compounds that accumulate in conjunction with a variety of conditions. And a team at the VIB-KU Leuven Center for Brain & Disease Research has seized on this technology to understand a protein complex that is common in patients with Alzheimer’s disease and with cancer. The γ-secretase complex is an enzyme composed of catalytic presenilin (PSEN), nicastrin (NCT), anterior-pharynx defective 1 (APH1), and presenilin enhancer 2 (PEN2) in a 1:1:1:1...Read full article

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