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Tailoring cancer therapy with the help of PCR analysis

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Gary Boas

In the latest campaign in the struggle against cancer, researchers are working to devise ways to individualize cancer treatment. One attempt involves therapies that block the epidermal growth factor receptor. Signaling of this receptor leads to increases in proliferation, angiogenesis and metastasis, and to decreases in apoptosis. Clinical trials have shown that compounds such as gefitinib and erlotinib effectively inhibit epidermal growth factor receptor activity, but the factors that determine and predict their efficacy — knowledge that could aid in individualization of treatment...Read full article

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    Published: November 2006
    BiophotonicsResearch & Technology

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