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Transparent Chip Provides View to Multimodal Imaging

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JOEL WILLIAMS, ASSOCIATE EDITOR
[email protected]

A transparent, biocompatible ultrasound transducer chip developed by researchers from Penn State is opening opportunities in cell and tissue stimulation and multimodal imaging. The chip, called a transparent ultrasound transducer (TUT), resembles a microscope slide and exhibits greater than 80% transparency. Cells can be cultured and stimulated directly on top of the transducer chip, and the cells’ resulting changes can be imaged with optical microscopy techniques. “In the conventional ultrasound stimulation experiments, a cell culture dish is placed in a water bath, and a...Read full article

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    Published: March 2022
    Glossary
    photoacoustic imaging
    Abbreviated PAI. An imaging modality with a hybrid technique based on the acoustic detection of optical absorption from endogenous chromophores or exogenous contrast agents. Light is absorbed by the chromophores and converted into transient heating, and through thermoelastic expansion there is a resulting emission of ultrasonic waves. In tissue, ultrasound scatters less than light, therefore PAI generates high-resolution images in the diffusive and optical ballistic regimes compared to purely...
    cell
    1. A single unit in a device for changing radiant energy to electrical energy or for controlling current flow in a circuit. 2. A single unit in a device whose resistance varies with radiant energy. 3. A single unit of a battery, primary or secondary, for converting chemical energy into electrical energy. 4. A simple unit of storage in a computer. 5. A limited region of space. 6. Part of a lens barrel holding one or more lenses.
    transducer
    A transducer is a device or component that converts one form of energy into another. It is commonly used in various fields, including electronics, acoustics, and instrumentation, to facilitate the measurement, detection, or transmission of information. Transducers are essential in converting signals from one domain to another for processing or interpretation. Key points about transducers include: Energy conversion: Transducers convert energy from one form to another. The input energy can be...
    transparent
    Capable of transmitting light with little absorption and no appreciable scattering or diffusion.
    Research & TechnologyOpticsMicroscopyImagingmultimodalphotoacoustic imagingphotoacousticBiophotonicsCellstimulationultrasoundslidetransducertransparentPenn Statelab on a chipOptics LettersAmericasBioScan

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