Scientific cameras have steadily progressed toward the physical limits of detection, under constant pressure to improve their ability to quantify and extract more information. Now, high-speed, high-resolution cameras are proving exceptionally versatile, offering near-perfect sensitivity.ROBERT LABELLE, PHOTOMETRICS and QIMAGINGSensors and cameras continue to progress, although life sciences imaging remains far from perfect. Even in its current state, barriers still exist. These include signal photon noise, light scattering, optical blur of finite aperture imaging systems and others. Versatile high-speed, high-resolution...Read full articleRelated content from Photonics MediaARTICLESSmartphone Fluorescence Microscopy Allows Cost-Effective Molecular DiagnosticsLack of diagnostic tools in resource-limited settings remains one of the major obstacles to disease diagnosis and treatment in the developing world. Although significant progress has been made in the...BioPhotonics August 2017 IssueSmartphone Spectroscopy Takes the Lab to the PeopleBy 2020, the number of smartphone users in the world is expected to reach almost 2.9 billion — nearly doubling in six years from about 1.6 billion in 2014. Technology companies and researchers...BioPhotonics October 2018 IssueShining a Light on Skin CancerA consortium of European scientists has developed what they’re calling the world’s first skin cancer scanner: a device — called VivoSight — that is capable of detecting blood...BioPhotonics March 2018 IssueLuminate NY Names Double Helix Top Winner of Competition's First RoundDouble Helix Optics was named the overall winner in the first round of the Luminate NY competition. The Boulder, Colo.-based company will receive $1 million in follow-on funding from New York state...BioPhotonics August 2018 IssuePRODUCTSDrug Formulation CameraThe FlowCam Nano from Fluid Imaging Technologies Inc. enables biopharmaceutical scientists to assess the colloidal stability of drug formulations to determine their resistance to aggregation over...BioPhotonics April 2018 IssueCMOS CameraThe Microscopy ace camera from Basler AG offers 12.2 MP with up to 15 fps with the latest Sony STARVIS IMX226 rolling shutter CMOS sensor. The camera uses backside-illuminated pixels and...BioPhotonics June 2018 IssueIR CamerasThe ZephIR line of IR cameras from Photon Etc. Inc. encompasses InGaAs and HgCdTe super-sensitive detectors up to a wavelength of 1.7, 2.5 or 2.9 μm. The high-grade cameras allow for new and...Photonics.com 5/19/2017CMOS CamerasBasler AG has announced the ace U and ace L CMOS cameras with high values for dynamic range, dark noise and quantum efficiency in low-light and high-speed applications. The ace U cameras with...Photonics.com 2/8/2018MEDIALight Matters Extra: Taking Photonics Innovations from the Lab to the Operating Room - 01.2018In this month's Light Matters Extra, we give you an in-depth look at the relationship between researchers and scientists at the University of California Davis, and surgeons and clinicians at nearby...Photonics.com 1/18/2018Photonics on the Showroom Floor and in the Lab - LIGHT MATTERS 02.2018On this month's episode of Light Matters, we take you on a brief tour of the Higgins Laboratories at Worcester Polytechnic Institute (WPI). Quinsigamond Community College and WPI received a $4M grant...Photonics.com 2/21/2018Supporting the Photonics Industry from the Laboratory - LIGHT MATTERS 01.2018On this month's episode of Light Matters, we take you to central Massachusetts as Worcester Polytechnic Institute and Quinsigamond Community College take on a comprehensive joint photonics laboratory...Photonics.com 1/18/2018Fundamentally Different Photonics - LIGHT MATTERS 03.2018On this month's episode of Light Matters, we take you to the South by Southwest (SXSW) Trade Show in Austin, Texas, as new photonics innovations hit the show floor of the Austin Convention Center....Photonics.com 3/29/2018WHITEPAPERSIs It True That Cooled Cameras are More Sensitive than Non-cooled Cameras?The temperature has a significant impact on certain noise sources prevalent in cameras, which contribute to the total readout noise of an image sensor. When electronic devices are operated...Photonics.com 3/19/2019Resolution and Dynamic Range: How These Critical CCD Specifications Impact Imaging System PerformanceResolution and dynamic range are two important specifications to be considered when evaluating the capabilities of an imaging colorimeter, yet they are easily misconstrued. The common assumption is...Photonics.com 7/10/2017How Laser Quantum Measures and Reports Root Mean Square (RMS) % Noise ValueOne of Laser Quantum’s goals has always been to create lasers with the lowest possible noise. Intracavity frequency-doubled lasers have an inherent noise of about 3% RMS. Several techniques have been...Photonics.com 1/16/2019Camera-based Products - Benefits of an ISO13485:2016-Certified SupplierWhat advantages does a supplier certified according to the medical device standard ISO 13485:2016 offer to a manufacturer of camera-based medical products? Our White Paper describes the requirements...Photonics.com 4/22/2019WEBINARSTechniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...Photonics.com 3/21/2013Fast & Sensitive Camera Technologies – How to Choose the Best SolutionJoin us for a FREE webinar – Thursday, August 21, 2014, 1 - 2 p.m. EDT Dr. Orla Hanrahan has worked with Andor Technology as an Application Specialist in Life Science for the past four...Photonics.com 8/21/2014State-of-the-Art Ultrasensitive Imaging Technologies for Microscopy - Choosing the Best SolutionThe recent introduction of true scientific CMOS (sCMOS) technology has caused considerable speculation as to how interline CCD, Electron Multiplying CCD and sCMOS detection technologies compare. This...Photonics.com 12/1/2011High-Speed Imaging At and Beyond the Diffraction LimitHari Shroff, Ph.D., head of the Section on High Resolution Optical Imaging at the National Institute of Biomedical Imaging and Bioengineering (NIBIB), will speak on his lab's latest work to develop...Photonics.com 2/16/2017PHOTONICS DICTIONARY TERMSepifluorescence microscopyFluorescence imaging technique in which the excitation light from the objective is directed into the sample producing emission at all angles. Light emitted into the objective is measured allowing the...EDU.photonics.com 3/5/2018coded aperture imagingAn imaging process in which the single opening of a simple pinhole camera is replaced with many openings called, collectively, the aperture. The recorded picture, which consists of many overlapping...EDU.photonics.com 9/8/2009noise equivalent delta temperature (NEDT)In a thermal imaging system, the change in temperature that yields a signal-to-noise ratio of unity.EDU.photonics.com 9/8/2009dark frameA frame taken to identify electronic noise in a CCD imaging device. A dark frame is recorded without exposing the CCD to any external light by, for example, leaving the shutter of a CCD camera...EDU.photonics.com 9/8/2009PHOTONICS HANDBOOK ARTICLESFluorescence Lifetime Imaging: Choosing the Best Approach: Fluorescence lifetime imaging microscopy (FLIM), which measures the spatial distribution of the fluorescence decay, can be achieved either in the time or in the frequency domain. Each approach exhibits advantages and disadvantages, depending on the type of light detector and acquisition method employed.The term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookPolarization-Based Imaging: Basics and Benefits: With spatial correction, line scan polarization cameras detect birefringence, stress, surface roughness and physical properties that cannot be detected with conventional imaging.There are three fundamental properties of light: intensity, wavelength and polarization. Almost all cameras today are designed for monochrome or color imaging. A monochrome camera is used to measure...Photonics HandbookSuperresolution Microscopy: An Imaging Revolution: Despite tremendous accomplishments in recent years, superresolution microscopy is a relatively young field, and confusion exists in this domain of many abbreviations. However, this makes for captivating times as superresolution microscopy opens the door to wider imaging applications.Superresolution optical microscopy has been one of the most momentous developments in the life sciences over the last decade — and its evolution is ongoing. Progress has been so rapid and...Photonics HandbookImage Quality Testing: Camera Advances Push Improvements: An overview of state-of-the-art technology for image quality testing of mass-produced camera modules for consumer devices, including recent developments and new challenges.Image quality testing of complete cameras and assembled camera modules is standard in the optics industry. It is done by imaging a suitable target using the camera module under test and evaluating...Photonics HandbookPHOTONICS BUYERS' GUIDE CATEGORIESSlow Scan CamerasAutocorrelatorsAn autocorrelator is a signal-averaging device that improves signal-to-noise ratio by comparing a sampled signal with a time-delayed form of itself.Ultraviolet MicroscopesAn ultraviolet microscope is a microscope used either to detect selective absorption of various wavelengths by the specimen or to achieve increased resolution by virtue of the short wavelength of...Machine Vision SystemsCOMPANIESPCO-TECH Inc.PCO – three decades as Pioneers in Cameras and Optoelectronics PCO is a Pioneer in Cameras and Optoelectronics with more than 30 years of expert knowledge and experience developing and...Photonics Buyers' GuideTeledyne DALSA, Machine Vision OEM ComponentsFor over 30 years, Teledyne DALSA has delivered industry-leading technology for digital imaging and specialized semiconductor fabrication. With core competencies in CCD and CMOS imagers,...Photonics Buyers' GuideAllied Vision Technologies GmbHABOUT US For more than 25 years, Allied Vision has helped people see the bigger picture to achieve their goals. We believe knowledge is power and always strive to deliver valuable insight with...Photonics Buyers' GuidePhotron USA Inc.Photron has been a global market leader in high-end, high-speed camera systems for over forty years. The company’s continuing development of new state-of-the-art products illustrates a...Photonics Buyers' Guide