Search Menu
Photonics Media Photonics Buyers' Guide Photonics EDU Photonics Spectra BioPhotonics EuroPhotonics Industrial Photonics Photonics Showcase Photonics ProdSpec Photonics Handbook
More News
Email Facebook Twitter Google+ LinkedIn Comments

Spectroscopy Combo Ups Diagnostic Accuracy

Dec 2014
A new spectroscopy technique can identify melanoma with as much as 93 percent accuracy.

Discovered by a team from the Institute of Electronics at the Bulgarian Academy of Sciences and University Hospital, the new method uses light-induced autofluorescence spectroscopy (LIAFS), which can detect biochemical changes that occur in skin disorders, as well as diffuse reflectance spectroscopy (DRS), which reveals morphological changes and the presence of diagnostically important skin pigments. Combining the two techniques increases diagnostic accuracy as compared to using each one separately, the researchers said.

The researchers looked at skin lesions (benign, dysplastic and malignant), initially identifying them with a dermatoscope and ABCD (asymmetry, border irregularity, color unevenness, diameter) criteria. Next, they measured the LIAFS spectra of the lesions and surrounding unaffected skin via excitation at 365, 385 and 405 nm from narrow-band LEDs. DRS data was obtained using a broadband (400-900 nm) halogen lamp.

This new combined optical approach improved diagnostic accuracy for normal and diseased tissue by using complementary information from each spectroscopy technique, the researchers said. Specifically, it can detect changes that appear in cutaneous non-melanoma and melanoma tumors and can accurately differentiate dysplastic and benign pathologies.

The researchers plan to use the LIAFS/DRS technique to study skin neoplasia. They are also working to integrate the new approach into a user-friendly device for medical professionals.

The work was funded by a grant from the National Science Fund of Bulgaria. The research was published in the SPIE journal Biomedical Optics & Medical Imaging (doi: 10.1117/2.1201405.005509). 

For more information, visit

BiophotonicsBioScanBulgariaDiffuse Reflectance SpectroscopyDRSEuropeimagingLEDsmelanomaopticsResearch & TechnologyspectroscopyInstitute of ElectronicsBulgarian Academy of SciencesTsaritsa Yoanna–ISUL University Hospitallight-induced autofluorescence spectroscopyLIAFSNational Science Fund of BulgariaEuro News

Terms & Conditions Privacy Policy About Us Contact Us
back to top
Facebook Twitter Instagram LinkedIn YouTube RSS
©2019 Photonics Media, 100 West St., Pittsfield, MA, 01201 USA,

Photonics Media, Laurin Publishing
x Subscribe to EuroPhotonics magazine - FREE!
We use cookies to improve user experience and analyze our website traffic as stated in our Privacy Policy. By using this website, you agree to the use of cookies unless you have disabled them.