CoolLED Ltd.

CoolLED designs and manufactures cutting-edge LED illumination systems for researchers and clinicians using the latest LED technology. The company has specialized in fluorescence microscopy since it introduced the first commercially available LED illumination system in 2006. CoolLED offers a comprehensive range of LED illumination systems for bioscience and clinical microscopy including:

pE-100 series – A mercury-free family of compact and simple to use LED illumination systems which can be configured to deliver light directly to a microscope, or via a liquid lightguide or multimode fiber. Systems can be specified at any one of 20 different LED wavelengths. Operation is by a remote manual control pod with instant on/off and intensity control from 0-100%. Remote control is available via a TTL trigger.


pE-300 Series – A compact range of triple wavelength LED illumination systems for fluorescence, Optogenetics, Electrophysiology and other high-speed applications designed to fit all major microscopes and with the broadest range available of software control. pE-300lite, a Simple White Light – simple to buy, fit and use. pE-300white provides a broad spectrum of LED illumination, covering the excitation bands of common fluorescent stains. Instant on/off and intensity control from 0-100%. Remote control is available via USB or TTL trigger.  pE-300ultra - most controllable member of the pE-300 Series which offers precise control over individual wavelength intensity and triggering.

pE-340fura – Bespoke LED illuminator for Fura-2 ratiometric calcium imaging, which also supports everyday fluorescence microscopy in a compact affordable package. The 340nm and 380nm system provides optimum excitation wavelengths for Fura-2 allowing high-precision, stable, high throughput imaging with video-rate time resolution.



pE- 4000 – Sets the standard as the universal illumination system for fluorescence microscopy. The system has 16 selectable LED wavelengths that can be matched to the filters and fluorophores of almost any microscope, making it the broadest spectrum of illumination available. For the user who wants consistency and ease of use with simple on/off and intensity buttons, the pE-4000 can be operated as a ‘White’ illumination system. For the user who wants total control over the excitation source to improve imaging, individual wavelengths settings can be selected and controlled in “Advanced” mode.