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tip-enhanced Raman spectroscopy: A spectroscopic technique that combines the high chemical specificity of Raman scattering and signal sensitivity provided by surface plasmon resonance enhancement, with the nanoscale spatial resolution of scanning probe microscopy (SPM). Supported by a sharp metallized-SPM tip, tip-enhanced Raman spectroscopy (TERS) enables label-free detection of surface components in multicomponent samples with ultrahigh spatial resolution, making it suitable for studying nanomaterials.

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