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BioPhotonics - October 2015
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Issue Library
Digital Edition
Features
MPEF Microscopy Shines Best on Living Samples
MPEF microscopy, along with other nonlinear methods that include coherent anti-Stokes Raman scattering (CARS), stimulated Raman scattering (SRS) and second harmonic generation (SHG), is suitable for...
In Vivo Neural Imaging — SLMs for Conducting 3D Holography inside Living Brains
The brain truly is a marvelous wonder of biology. With an extensive range of functions and dynamics that span many length scales and timescales, it is also marvelously complex. By better...
OPSLs — Unique Benefits Driving Growth in the Life Sciences
In an OPSL, laser diodes are used to pump a thin semiconductor chip, thus enabling an incredible level of design flexibility in terms of power and wavelength scalability. The quantum well structure...
Reduced to the Essentials — Portable Imaging Gets High-Tech
It takes some clever thinking to shrink many of the cumbersome biological imaging tools in use today to a size where they can be taken directly to the bedside. For some patients, point-of-care...
Editorial
Light-Based Technologies — A Way of Life
From the lab to the clinic, light-based technologies aren’t trends. They’re well-planted ways of life for those who develop them and a proven means of bettering the lives of those who access them. Like any technology, they improve over time, becoming increasingly refined with each iteration and less costly as the components they comprise become cheaper to produce. What was just a...
BioScan
Modified SIM Makes Movies of Cell Processes
Variations on structured illumination microscopy (SIM) provide a way to watch dynamic biological processes inside living cells with unprecedented clarity. "These methods set a new standard for how far you can push the speed and noninvasiveness of superresolution imaging," said Nobel laureate Dr. Eric Betzig. "This will bring superresolution to live-cell imaging for real." A group leader at the...
Light Triggers Stem Cell Differentiation
Blue light can trigger the transformation of embryonic stem cells into neurons. Based on optogenetics techniques, the discovery could be a first step toward complex tissue engineering using light,...
Montana Invests in Optics for Agriculture
Recently announced state funding aims to kick hyperspectral imaging into hyperdrive. Montana State University researchers aim to develop new technology for Resonon Inc., a manufacturer of machine...
Thermal Issues Associated With Flow Cytometry Miniaturization Solved
Positioning equipment supplier Siskiyou Corp. said it recently helped another manufacturer miniaturize its cytometry system by developing adjustable mounting hardware that conducts heat away from the...
Implantable Optogenetics Device Powered Wirelessly
Combining optogenetics and wireless energy transfer technology, a new device is said to be the first fully implantable platform for optical neural stimulation. The device dramatically expands the...
Method Lends 'True Color' to Superresolution Microscopy
Building on earlier superresolutions methods, a new microscopy technique provides nanoscale spatial information on individual molecules while also revealing their spectra. SR-STORM, or spectrally...
Adjustable-Focus Endoscope May Reduce Colonoscopy Discomford
An endoscopic probe with adjustable-focus capabilities in a slim package could facilitate more effective and less painful colonoscopies. Researchers at the National University of Singapore (NUS)...
Gas-Sensing MEMS Interferometer Connects to Smartphones
Air and sleep quality can be gauged by an optical gas sensor that attaches to smartphones. The VTT Technical Research Centre of Finland developed the device, which is based on Fabry-Perot...
LED Heating, Cooling Method Enables Ultrafast DNA Diagnostics
Developed by bioengineers at the University of California, Berkeley (UC Berkeley), an advanced thermal cycling system is expected to expand clinical and research applications associated polymerase...
RapidScan
Firm Secures Grant to Develop Microscope
A $744,066 federal grant will aid further development of a microscope whose ability to detect cellular motion could be of use in testing drugs. Based on fluorescence imaging and spectroscopy techniques, the biodynamic microscope is being developed by Animated Dynamics Inc. (AniDyn), a Purdue University spinoff. The two-year, $744,066 Small Business Innovation Research (SBIR) Phase II grant was...
Student Wins Award for Laparoscope Design
Designs for imaging systems to explore distant worlds and aid abdominal surgery are among the winning entries in an annual student contest sponsored by Synopsys Inc. The annual Robert S. Hilbert...
Heidelberg Engineering Licenses OCT Ophthalmology Technology from Mass General
Heidelberg Engineering Inc. plans to develop new ophthalmology products based on optical coherence tomography (OCT) under a licensing agreement with Massachusetts General Hospital. The agreement...
Markus Hersche Named CEO of Fisba
Optics manufacturer Fisba AG has named Markus Hersche its new CEO. Taking over the responsibilities of Managing Director Werner Krüsi, Hershe moves into the management role from the supervisory...
David Williams Wins $500K to Advance Adaptive Optics, Human Vision Research
A pioneer in the use of adaptive optics to improve human sight, University of Rochester professor David Williams has received the 2015 Beckman-Argyros Award in Vision Research. The award is given...
'Biochemical Nose' Targeted for Home Sensing Market
A "biochemical nose" based on Raman spectroscopy can quickly and accurately detect or diagnose substances at the molecular level for applications in food safety, medical diagnosis, chemical analysis...
Auffarth, Blumenkranz Named to Presbia Boards
Presbia PLC, an ophthalmic device company, has appointed Dr. Gerd Auffarth to its Board of Directors and Dr. Mark Blumenkranz to its Medical Advisory Board. Dr. Auffarth is the director of the...
Postscripts
Smart Light Captures Body in Motion
Using solely the visible light around us, a new light-sensing system tracks whole-body human postures unobtrusively and in real time. The LiSense system reconstructs a 3D skeletal model on a computer screen based on the shadows cast by a person moving within a lighted room — no cameras or on-body devices required. “Light is everywhere, and we are making light very smart,” said...
Products
Chambered Coverslip
A chambered microscope coverslip from ibidi GmbH is designed for relocating and counting cells or cell clusters. The μ-Slide 8 Well Grid-500 combines a well designed for cell culture and high-resolution microscopy with a laser-imprinted grid with a 500-μm repeat distance. Sample observation can be achieved through a polymer coverslip bottom, while small numbers of cells and low...
ibidi GmbH
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Laser Scaler
The SB10 Sea Beam laser scaler from Laser Tools Co. Inc. is a waterproof device that can measure size from a distance of 600 ft. The SB10 directs two laser beams 75 mm apart, allowing...
Laser Tools Co. Inc.
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Bright-Field LEDs
Prior Scientific Instruments Ltd. has announced the LDB100F and LDB101F LEDs, replacing standard light sources and reducing background fluorescence for brightfield microscopy. Direct coupling...
Prior Scientific Instruments Ltd.
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Microscope Stages
The PInano stage series from PI (Physik Instrumente) LP offers high stability and linearity for superresolution microscopy. The stages are available with piezoresistive position feedback...
PI (Physik Instrumente) LP, Motion Control, Air Bearings, Piezo Mechanics
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Femtosecond Laser
A compact, turnkey system for bioimaging applications, a new laser from Toptica Photonics Inc. provides femtosecond pulses with high average power and beam quality in the near-infrared range. ...
TOPTICA Photonics Inc.
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NIR Camera
Princeton Instruments Inc. has announced the NIRvana:640LN, a scientific-grade camera for near- and shortwave-infrared applications. An InGaAs focal plane array provides extremely low readout...
Teledyne Princeton Instruments
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Spectral Sensor
Pixelteq Inc. has announced its PixelSensor spectral sensor with a new OEM electronics board. PixelSensor has a small footprint and is designed for integration into analytical equipment. A...
Pixelteq
UV LED
Solid State Supplies Ltd. has announced the LZ4-04UV00 LuxiGen emitter, combining a surface-mount package with the latest generation of high-power UV LED die. The device emits at 365-nm...
Solsta
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Wearable Sensor
The SFH 7060 sensor from Osram Opto Semiconductors GmbH is designed for use in devices that measure pulse rate and the oxygen saturation level of blood. The device contains five LEDs with three...
Osram Opto Semiconductors GmbH
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UVC LED
The Optan surface-mount device from Crystal IS Inc. features an LED emitting in the ultraviolet C (UVC) band for use in underwater applications. The device is based on native aluminum nitride...
Crystal IS Inc.
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Illumination System
The Lumen 200S metal halide illumination system from Prior Scientific Instruments Ltd. is an alternative to standard 100-W mercury and halogen lamp houses traditionally used for fluorescence imaging....
Prior Scientific Instruments Ltd.
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Cell-Imaging Systems
Microplate instrumentation manufacturer BioTek Instruments Inc. has added a patent-pending laser autofocus feature to its Cytation cell-imaging multimode readers. The autofocus design compiles...
BioTek Instruments Inc.
UV Disinfection System
Heraeus Noblelight America LLC has announced the Heraeus Premium UV disinfection system for food packaging surfaces. The UV lamp has a service life of up to 12,000 operating hours and reduces...
Heraeus Noblelight America LLC
CCD Cameras
QImaging, part of Roper Industries Inc., has announced the Retiga series of CCD cameras for microscopy and imaging. The cameras feature deep cooling that virtually eliminates dark-current...
Teledyne QImaging, Teledyne Imaging
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Multilaser Engine
Toptica Photonics Inc. has announced the iChrome SLE multilaser engine, a field-upgradeable, eight-color laser engine for multicolor microscopy and other biophotonic applications. The iChrome...
TOPTICA Photonics Inc.
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Interferometric Thickness Gauges
The 137 series of interferometric thickness gauges from Bristol Instruments Inc. measures absolute thickness to an accuracy of ±1 μm with a repeatability of ±0.05 μm. The...
Bristol Instruments Inc.
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Clinical Microscope
Leica Microsystems GmbH has announced the DM2500 LED microscope for clinical laboratories and research applications. Ultrabright LED illumination offers a constant color temperature at all...
Leica Microsystems GmbH
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12-MP CCD Cameras
Point Grey Research Inc. has announced the 12-MP Grasshopper3 GS3-U3-120S6 CCD vision cameras, based on color and monochrome versions of the 1-in. Sony ICX834 global shutter CCD sensor. The...
Teledyne FLIR Integrated Imaging Solutions
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Picosecond Lasers
Offering ultrashort pulse widths optimized for microscopy applications, the VisIR-765 STED (pictured) and VisUV lasers from PicoQuant GmbH are based on a master oscillator fiber amplifier concept...
PicoQuant GmbH
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CMOS Cameras
PixeLink has announced the PL-D752 and PL-D792 CMOS cameras, two new, 2.3-MP global shutter CMOS models for its family of USB 3.0 vision cameras. The new cameras are based on Sony's IMX174 and...
Pixelink
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Direct Diode Laser
Designed for powering bioinstrumentation, a new direct diode laser from Spectra-Physics (a Newport company) has a bandwidth at least three times narrower than conventional 488-nm direct diodes. The...
MKS/Spectra-Physics
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Fluorescence Lifetime System
The Ultima time-correlated single-photon counting (TCSPC) fluorescence lifetime system from Horiba Scientific (a division of Horiba Instruments Inc.) is optimized for short-lifetime measurements with...
HORIBA
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Medical Imaging Sensor
OmniVision Technologies Inc., Precision Optics Corporation Inc. (POC) and Fujikura Ltd. collaborated to produce a 160K CMOS imaging sensor (CIS) module for medical imaging OEMs. The module has...
OMNIVISION
Precision Optics Corp.
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