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BioPhotonics: August 2006

BioPhotonics
 August 2006


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FEATURES
Getting to the Core At Harvard Medical School in Boston, Jennifer Waters is quite popular at times, especially when she’s running a one-day training workshop for postdoctoral researchers. She and her staff teach the course every two weeks, and that isn’t often enough. “The demand is just unbelievable,” she said. “We have a constant wait list for all of the courses. We can’t teach...
A Medical Diagnostic Application of Raman Multimodal Multiplex Spectroscopy The new and rapidly expanding field of nanoscale medical diagnostics requires the development of advanced sensor technologies to provide the selectivity and sensitivity needed to measure...
Improving Capillary Electrophoresis the Photonic Way As a tool for divining all that is knowable about proteins, capillary electrophoresis has taken a strong grip on investigators. The technique offers scientists from oncologists to pharmacologists...
RAPIDSCAN
Luminosity in the eyes of the beholder The human eye takes significant cues from visual contrast within a woman’s facial skin to evaluate her age, health and attractiveness according to a study by researchers at Ludwig Boltzman...
Dual-beam fiber trap improves Raman microspectroscopy Raman spectroscopy is employed in many biomedical applications; however, it has several drawbacks. The low intensity of the emitted signal combined with the possibility of recording signals from the...
Hybrid SPECT/CT image reveals coronary lesions Five years ago, cardiac CT scanners had only four detectors. Today that number has jumped to 64. Cardiologists also can fuse CT with single-photon emission computed tomography (SPECT) images. Dr....
Researchers tag proteins with fluorescent amino acid Researchers at The Scripps Research Institute in La Jolla, Calif., have developed a way to genetically encode a fluorescent amino acid in a cell. The result is a fluorescent tag with a lower...
Fruit fly protein involved in circadian response to light When people travel across time zones, jet lag occurs because the body’s internal clock takes a long time to synchronize to a new day and night schedule. The internal clock, or circadian rhythm,...
Site-directed drug delivery Every drug carries a risk. Compounding that fact, drugs delivered by conventional methods can diffuse to unwanted areas. For that reason, Andre G. Skirtach and colleagues have developed a laser-based...
Surface adherent carbohydrate bolsters contrast magnetism agents The benefits of using higher magnetic field strengths in biomedical MRI have driven investigators to explore possibilities for more efficient contrast agents. An ideal agent would work with several...
MRI tested as detector of coronary artery disease Coronary artery disease, the leading cause of death in the US, occurs when the arteries that supply blood to the heart become hardened and narrowed from a buildup of plaque on their inner walls....
Minute cyanobacteria more gluttonous than once thought Researchers from Woods Hole Oceanographic Institution in Massachusetts have conducted a survey of the North Atlantic to determine the population and distribution of the colonial cyanobacteria (also...
Integra Biosciences AG Integra Biosciences AG of Chur, Switzerland, has signed a distribution agreement with Microbiology International of Frederick, Md., to improve North American sales and support. Integra is a...
Howard Hughes Medical Institute Howard Hughes Medical Institute of Chevy Chase, Md., has awarded California Institute of Technology of Pasadena $1.5 million to aid its undergraduate science education programs. The four-year grant...
Odyssey Thera Inc. Odyssey Thera Inc. of San Ramon, Calif., has been granted a US patent for its single- and multicolor protein-fragment complementation assays for drug discovery. The patent provides methods for...
Olympus America Olympus America of Center Valley, Pa., has entered into an agreement to purchase Bacus Laboratories Inc. of Lombard, Ill., a developer of virtual microscope slide technology and software. The...
Invitrogen Corp. Invitrogen Corp. of Carlsbad, Calif., and Cellartis AB of Gothenburg, Sweden, will collaborate to create human embryonic stem cell reporter lines. This will allow tracking of cell lineage and the...
Mercury Computer Systems Inc. Mercury Computer Systems Inc. of Chelmsford, Mass., will partner with FPS France of Rungis, France, Color Printer Systems of Germany and Medical Imaging PACS Pty Ltd. of Brisbane, Australia. The...
Getting to the Core At Harvard Medical School in Boston, Jennifer Waters is quite popular at times, especially when she’s running a one-day training workshop for postdoctoral researchers. She and her staff teach...
AS WE GO TO PRESS
PET/CT scan goes three-dimensional Doctors have several methods for detecting cancer in their patients, including PET and CT scans, PET/CT scans and three-dimensional CT scans. Although the technology enables physicians to pick up a metabolic signal from actively growing cancer cells, to generate a detailed image of internal anatomy, and to locate and reveal the size and shape of abnormal cancer growths, even the most...
MRI reveals brain activity during gambling People make risk-versus-reward decisions every day, whether making purchases or deciding how to travel to work. Despite the important role of risk in decision-making, neuroscience studies have...
PDT demonstrated without external light Photodynamic therapy (PDT) selectively destroys cancer cells using an external light source, such as a laser. Because external light cannot penetrate internal tissue, doctors must perform invasive...
Optical trapping of femtoliter droplets To develop effective drugs, researchers need to identify which molecules interact and what conformations they adopt when they do so. Isolating molecules simplifies their study but requires chemically...
New contrast agent infiltrates aorta Despite recent advances in detection and treatment, atherosclerosis — characterized by deposits in the inner layers of arteries — is still a major health concern worldwide. Noninvasive...
BREAKTHROUGHMEDIA
Pulsed UV light The advantages of pulsed UV light over continuous mercury UV lamps for curing applications are described in a brochure from Xenon Corp. The downloadable four-page publication notes that pulsed UV systems provide better penetration while maintaining low average power, and that they consume up to 80% less energy than the mercury types. A chart illustrates that pulsed UV light provides cooling...
Lab tools, eyewear Melles Griot Corp. has added laboratory accessories and laser safety eyewear to its online catalog. Supplies and equipment for the care, cleaning, handling and inspection of optical components are...
Metabolic profiling Bruker BioSpin Corp. has released the NMR Metabolic Profiling Database for metabolite identification and quantification. Developed collaboratively by Bruker, food and pharmaceutical companies, and...
Radiation dosimetry Covering applications, basic principles and advanced concepts in the discipline, the 219-page book Advanced Materials and Techniques for Radiation Dosimetry discusses radiation sensing using thin and...
Live-cell imaging Warner Instruments, a Harvard Apparatus Co., has published its 2006/07 catalog of specialized tools for electrophysiology and cell biology research. The 352-page, color-coded resource specifies new...
Digital camera site A redesigned Web site has been launched by Andor Technology plc, a supplier of digital cameras, spectrographs, microscopy systems, and related software and accessories. The portal offers improved...
Biosensing research The goal of the 416-page volume Biosensing: International Research and Development is to provide information on the status and trends of biosensing research worldwide to government officials and to...
Stem cell research The 100-page “Stem Cell Catalog 2006” from Chemicon International presents items for stem cell culture and pluripotent and multipotent stem cell research. Among them are numerous stem...
Biology reagents Bioline has released “Product Catalog 2006/7, Core Reagents for Molecular Biology.” The 121-page color-coded publication highlights new products such as the Trisure ready-to-use reagent...
Analytical instruments The “Consumables and Accessories 2006-2007 Catalog” from PerkinElmer Life and Analytical Sciences Inc. includes more than 5000 products for thermal analysis, atomic absorption, elemental...
Plate reader for HTS Wyatt Technology Corp. has issued a four-page brochure titled “The DynaPro Plate Reader for Automated, High Throughput Dynamic Light Scattering.” Available in hard copy or pdf, the...
POSTSCRIPTS
Unearthing the Neanderthal, digitally Some 30,000 years ago, people of the species known as Neanderthal inexplicably vanished from their habitat in Europe. Their much-debated legacy is survived by fossilized remains, of which the first were discovered in the Neander valley near Düsseldorf, Germany, 150 years ago. After this initial finding, numerous relics have been unearthed throughout Europe. The upper and lower jaws of...
PRODUCTS
Medical imaging sensor OmniVision Technologies Inc. has released a 1/18-in. CMOS image sensor for use in disposable cameras for medical applications such as intubation and diagnostic systems. The OV6920 2.1 x 2.3-mm chip scale package will make possible a camera module that is 3.2 mm in diameter. The module is expected to make many medical procedures less invasive for patients. It will enable the fabrication of smaller...
OmniVision Technologies Inc.
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OPD scanning system The OPD-Scan II ARK-10000 optical path difference (OPD) scanning system for human vision assessment has been unveiled by Nidek Co. Ltd., providing information on corneal topography, autorefraction,...
NIDEK CO. LTD.
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Laser diode modules Deepstar temperature-stabilized diode lasers produced by Omicron Laserage Laserprodukte GmbH offer modulation speeds of up to 100 MHz and modulation depth of greater than 100,000:1. Part of the LDM...
Omicron-Laserage Laserprodukte GmbH
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Fluorescence imaging The GelDoc-It TS high-resolution fluorescence imaging system from UVP Inc. offers touch-screen capabilities and a built-in computer and software, making it easier to select various settings,...
Analytik Jena US LLC
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Imaging controller Available from Nikon Instruments Inc., the Digital Sight DS-L2 imaging controller enables users to comfortably observe, record and use images. It features an 8.4-in. LCD monitor and can connect to a...
Nikon Instruments Inc.
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Surgical lamp The compact Celestial Star MRI surgical light from Sunnex offers a drift-free balance arm, flexible positioning around the bore and a 114-in. vertical and horizontal reach for head-to-toe coverage....
Sunnex Inc.
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Microscope controller The NanoScope V controller from Veeco Instruments Inc. extends the capabilities of the company’s scanning probe microscope systems, including the PicoForce and Dimension, NanoMan and MultiMode...
Veeco Instruments Inc.
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Vibration isolation Kinetic Systems Inc. will customize its vibration control mounts for applications where isolation from ambient vibration is required. Available in numerous sizes and configurations, the mounts are...
Kinetic Systems Inc.
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Digital camera Lumenera Corp. has launched the Lw290 camera, based on a 1080P sensor, which is suitable for medical imaging. The camera’s 16:9 high-definition, 2.0-megapixel CMOS sensor delivers 20 fps at...
Teledyne Lumenera
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Piezo controller The E-625 nanopositioning controller from PI (Physik Instrumente) LP was designed for the company’s Pifoc high-speed piezo-actuated Z-stack image acquisition drives. Z-stack acquisition is the...
PI (Physik Instrumente) LP, Motion Control, Air Bearings, Piezo Mechanics
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Gold-coated mirrors Newport Corp. has introduced protected gold broadband mirrors to its line of metallic mirrors. They are suitable for scientific research as well as aerospace and defense applications that use near-...
MKS/Newport
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Medical display The LMD-1950MD LCD monitor from Sony Electronics Inc. offers a viewable area that measures 19.1 in. diagonally. Suitable for endoscopy and other medical imaging applications, the display features a...
Sony Electronics Inc., Visual Imaging Products Group
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Imaging software Bruker Daltonics has announced two updated software versions, ClinProTools 2.1 and flexImaging 2.0. When integrated, the packages allow researchers to merge statistical analysis on Maldi-Tof...
Bruker Daltonics Inc.
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Amplifiers and lasers Toptica Photonics AG has released the TA-B series tapered amplifiers and TA-100 series laser systems. Suitable for interferometry, holography, Raman spectroscopy, and atom cooling and trapping, the...
Toptica Photonics AG
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NIR analyzer LT Industries Inc. has launched the SPX-II LT-NIR analyzer series. The line features single-compartment liquid and solid measurement capability with the LT OmniPhase sample compartment, the OpCon-II...
Verum Analytics
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Wide-field imaging Andor Technology plc has introduced the Revolution K-Series wide-field fluorescence/luminescence imaging devices for high-sensitivity live-cell imaging, fluorescent protein exploitation, ion imaging...
Andor Technology
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Ultrafast laser Available from Coherent Inc., the Micra ultrafast laser delivers more than 100 nm of broad spectral bandwidth and includes both a broadband oscillator and a Verdi pump laser. It can be used to seed...
Coherent Inc.
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Antireflection lenses Edmund Optics has expanded its in-stock selection of broadband antireflection-coated lenses. The 6.25-, 9.0-, 12.5- and 25-mm achromats are available with the VIS 0¼ multilayer broadband...
Edmund Optics Inc.
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Raman spectrometer B&W Tek Inc. has released the HandTop MiniRam, a portable device based on the MiniRam Raman spectrometer system with an added PDA-size computer. The computer uses the Microsoft Windows XP...
B&W Tek LLC
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Continuum generator Del Mar Photonics Inc. has announced the Jibe White Light Continuum Generator for use with ultrafast lasers in applications such as femtosecond time-resolved spectroscopy, microscopy, optical pulse...
Del Mar Photonics Inc.
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Miniature spectrometers StellarNet Inc. has released the NIRX-SR series spectrometers for laboratory and field measurements. Covering the 900- to 2200-nm wavelength range, the ruggedized miniature instruments feature a...
StellarNet Inc.
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Tunable ring laser The Matisse TS from Spectra-Physics, a division of Newport Corp., is a tunable CW single-frequency ring laser suitable for such scientific applications as high-resolution spectroscopy, and research...
Newport Spectra-Physics GmbH, Photonics Solutions Div.
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Polyimide-coated fibers A line of polyimide-coated optical fibers has been introduced by FiberLogix Ltd. The fibers are suited for use in applications where high strength and low bending loss are required, such as strain,...
FiberLogix International Ltd.
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Stop-action camera The 4M60 SA CMOS camera from Dalsa Corp. features stop-action, area-scan technology. The device provides 62 fps at its full 2352 x 1728-pixel resolution in 8- or 10-bit operation. It features...
Teledyne DALSA, Machine Vision OEM Components
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Laser source The id300 laser source from id Quantique SA generates short laser pulses at wavelengths of 780, 850, 1310 or 1550 nm. It is designed to work with the id200 single-photon-detection and -counting...
ID Quantique
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Keypad software Prior Scientific Inc. has implemented changes to its CS152KB touch-screen programmable keypad with multiple software enhancements. The mini-computer provides stand-alone control for the...
Prior Scientific Inc.
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Replicated gratings Replicated gratings for use in transmission are available from Optometrics Corp. in a variety of standard and custom sizes. With thickness and dimensional tolerances of ±0.5 mm, the blazed...
Optometrics Corp.
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BIOPHOTONICS 2006
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