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BioPhotonics: August 2016

BioPhotonics
 August 2016


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FEATURES
When the Camera Is a Computer: Computational Life Sciences Imaging Sensors and cameras continue to progress, although life sciences imaging remains far from perfect. Even in its current state, barriers still exist. These include signal photon noise, light scattering, optical blur of finite aperture imaging systems and others. Versatile high-speed, high-resolution systems are overcoming these and other challenges, moving microscopy into a diagnostic role. Figure...
High-Content Screening Goes Beyond Fluorescent Pictures Since the start of high-content screening (HCS) in the late 1990s, several imaging techniques have been applied for automated image capture, serving a variety of application goals and specifications....
New Quantum Dots Excite In Vivo Imaging Advancements New quantum dots made without heavy metals are poised to take optical in vivo imaging to the next level.
Neuroscience Driving Continued Growth in Multiphoton Microscopy More than half of the thousands of deployed multiphoton microscopes are used for neuroscience — in large part because of major funding initiatives across three continents. Some of these...
Member Exclusive
OCT Angiography Opens Eyes Dr. Daniela Ferrara, an assistant professor of ophthalmology at Tufts University School of Medicine in Boston, began researching retinal diseases in 1998. Age-related macular degeneration (AMD), a...
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EDITORIAL
Do No Harm Even though doctors are not bound to the requirement to do no harm, they should generally aim to inflict as little of it as possible, given the patient’s condition and circumstances. And this issue of BioPhotonics highlights how photonics are stepping in to help ophthalmologists to do just that.
BIOSCAN
Heat from Laser Ablation Treats Prostate Cancer A novel fusion-imaging technique uses MRI to guide the insertion of a laser fiber into a cancerous tumor. The laser, once inserted, applies heat to the cancerous tissue, destroying it. This technique, known as MRI-guided focal laser ablation, could improve treatment options and outcomes for men with prostate cancer. An illustration of how laser ablation is used to treat prostate cancer. Courtesy...
Fluorescent Biosensors Track Heme Activity in Cells Genetically encoded fluorescent sensors are providing a way to track the mobilization of labile heme in cells. The sensors offer significant insight around the nature and dynamics of this potentially...
Optogenetic Technique Screens for Cardiac Drug Safety An optogenetic technique has been used to make cardiac cells beat and optically measure their response, enabling an automated drug-testing process called OptoDyCE.
Nanoblade Enables Mitochondrial DNA Transfer Laser-powered nanoblade technology typically used to transfer materials between cells has now been used to slice through a cell’s membrane to enable the insertion of mitochondria. Other...
FLIM OPT Live-Monitors Cell Signaling Fluorescence Lifetime Imaging (FLIM) combined with Optical Projection Tomography (OPT) has been used to image and monitor apoptosis in whole live organisms in 3D. Termed FLIM OPT, the method may...
Collagen Crosslinking Demonstrated for Corean Repair A technique called two-photon collagen crosslinking (2P-CXL) has been demonstrated to strengthen the cornea, with results confirmed by confocal Brillouin microscopy. The method could enable selective...
Optofluidic Lab-On-A-Chip Measure Glucose The lab-on-a-chip approach is being applied to the development of glucose meters for the early diagnosis and prevention of diabetes. An optofluidic device has enabled detection of glucose in...
Rhodopsin Mimic Advances Light-Sensitive Cell Design An artificial mimic of a key light-sensitive molecule could enable techniques for building light-sensitive artificial cells. Professor Jonathan Clayden and colleagues in the University of Bristol's...
Laser Achieves Multimodal Imaging With a Single Source A solid-state degenerate laser system that can provide efficient methods of coherence switching has been used to provide both speckled and speckle–free images. The technology enables...
RAPIDSCAN
Ultratech-CNT, Northeastern Collaborate on Medical Nanomaterials Lithography and laser system supplier Ultratech Inc. has announced a research collaboration with Dr. Thomas J. Webster at Northeastern University in Boston, to study the use of nanomaterials produced via adrenoleukodystrophy (ALD) for medical applications. "We are very excited to embark on this collaboration with Ultratech-CNT,” Webster said. “While we are in the early stages of this...
Dynasil Subsidiary RMD Receives $3.8M in Government Grants RMD Inc., a contract research subsidiary of optical solution developer Dynasil Corp. of America, has received six grants totaling $3.8 million from NASA, the National Institute of Health (NIH) and...
Fluence Demonstrates Advanced LED Grow Lights Fluence Bioengineering, a photobiology design and manufacturing company, has developed an indoor and greenhouse LED lighting system with an efficacy above 2 μmol/J according to replicate,...
Toptica to Support Life Sciences Laser Miniaturization Project Toptica Photonics AG said it will provide semiconductor laser sources and integration services to PIX4life, a pilot line focused on the development of a compact, fully integrated photonics device to...
On Target Closes $5.2M in Funding On Target Laboratories LLC, whose fluorescent imaging technology enables surgeons to identify and remove more cancerous tissue than previously possible, said it has received $5.2 million in private...
THE PIPELINE
Biophotonics Cos.’ R&D Spending Strong Out of the Gate in FY2016 Research and development (R&D) spending at many biophotonics-related companies grew at a robust pace during the first three months of their 2016 fiscal years, though a key R&D metric slipped slightly amid even stronger revenue growth, according to a Photonics Media analysis of 20 publicly traded companies’ quarterly financial reports. During their first quarters, which had end dates...
POSTSCRIPTS
Star Wars Meets Mosquito Control What does it take to kill a mosquito? How about thousands of them? Since 2010, Bellevue, Wash.-based Intellectual Ventures Management LLC has been working on answers to these questions. Their solution: the Photonic Fence, a laser system that optically tracks all flying insects that enter a coverage area and zaps only those identified as threats, namely mosquitoes. However, it was only recently...
PRODUCTS
sCMOS Detector Andor Technology Ltd., an Oxford Instruments company, has launched launch the iStar scientific CMOS (sCMOS) platform. The device combines superfast frame rate capabilities >4000 fps, high...
Andor Technology
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CMOS Camera Spot Imaging has announced the Insight CMOS Camera featuring Sony’s Pregius sensor. The camera’s USB 3.0 interface and global shutter work with a software autoexposure scheme to...
SPOT Imaging
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Mounting Wings Prior Scientific Instruments Ltd. has announced accessory mounting wings for its H117 stage for inverted microscopes. The wings enable simple, precise integration of tools such as microfluidic...
Prior Scientific Instruments Ltd.
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ZnSe Optics Laser Research Optics has introduced laser-grade zinc selenide (ZnSe) optics that can be fabricated to specification for medical laser OEMs in 0.5- and 0.75-in. sizes, and can be supplied with...
Laser Research Optics
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Bio-Optical Sensor Anitoa Systems LLC has announced the ULS24 Ultra Low-Light CMOS Bio-Optical Sensor, capable of detecting a few ng/ML of analyte in a sample. The device features a proprietary ULS24 CMOS...
Anitoa Systems LLC
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Microscopy Video Camera The IL5, a 5MP camera from Fastec Imaging, can be mounted on a microscope to enable high-speed video recording of microscopic events. Four models offer resolution and rates from 2560 × 2080 at...
Fastec Imaging Corp.
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Microscopy Cube Service Semrock offers installation service of its 1-mm dichroic beamsplitters — designed to minimize reflected wavefront distortion for illumination beams — in commercial, off-the-shelf...
IDEX Health & Science - Semrock Optical Filters
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Live Cell Imaging System Oxford Nanoimaging Ltd. has announced the Nanoimager, a desktop, nanoscale imaging system for live cells. The Nanoimager can measure the dynamics of molecular interactions and structural...
Microscopy System Witec GmbH has announced the alpha300 access micro-Raman system in conjunction with a revision of its alpha300 series. The access microscope is an entry-level system for micro-Raman ,...
WITec GmbH
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Lens Controller Optotune Switzerland AG and Gardasoft Vision Ltd. have announced the TR-CL series of single-channel industrial lens controllers for the Optotune EL-10-30 and EL-16-40 focus-tunable lenses. ...
Optotune AG
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Light-Sheet Microscope Lavision BioTec GmbH has announced the latest UltraMicroscope II system, combining macro imaging capabilities with cellular resolution to allow 3D imaging of cleared samples in aqueous and organic...
LaVision BioTec GmbH
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Linear Array Detectors Ames Photonics has announced the LARRY USB series of linear array detectors, offering cost-effective, scientific-grade performance for a wide range of spectroscopic applications. The devices...
Ames Photonics Inc
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Microscopy Package Basler AG has announced the PowerPack for Microscopy, offering high-quality cameras and CMOS sensors with resolutions from 1.2 to 5 MP. Up to 82 images are captured per second for complete and...
Basler AG
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Crossed Roller Stages The 50.5cr crossed roller stages from Siskiyou Corp. are designed for space- or weight-constrained applications. The stages feature a noninfluencing foil lock mechanism, and offer a linear travel...
Siskiyou Corp.
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Microscopy Cage Neurotar Oy’s Mobile HomeCage is an accessory device for microscopy and electrophysiology, enabling high-precision tests in the brain of awake, head-fixed, but otherwise freely moving rodents....
Neurotar
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Microscope Cameras Jenoptik AG has announced the Progres Gryphax Arktur and Naos cameras for routine microscopy use. With a high light yield and wide dynamic range, subjects can be explored at a very low noise...
Jenoptik Optical Systems GmbH, Optical Systems
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BIOPHOTONICS 2016
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