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BioPhotonics: February 2007

BioPhotonics
 February 2007


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FEATURES
Probes Light the Way for Advances in FRET First described almost 60 years ago, Förster resonance energy transfer (FRET) traditionally uses two molecules — donor and acceptor — to visualize biological activity. Today the technique continues...
Ultrafast, Ultrawide-Band Spectroscopy The interdisciplinary study of molecular science aims to expand our knowledge of everything around us, from the molecular bonds that give plastic widgets their strength to the electron transitions...
AS WE GO TO PRESS
Imaging reveals intracranial bleeding in asymptomatic newborns A recent neonatal brain development study led by Dr. John H. Gilmore of the University of North Carolina School of Medicine at Chapel Hill used MRI to assess intracranial hemorrhage in 88 babies...
Flaws discovered in oncology microarray studies Scientists generally classify microarray analysis as a type of discovery-based research. As with hypothesis-based procedures, such research must incorporate sound principles of statistical analysis...
An ultrasensitive and ultraselective uranium sensor Uranium poses a threat to human health and the environment, but the most sensitive methods of uranium detection require costly and bulky laboratory instruments. Therefore, keen analysis currently...
Gadolinium-based MRI contrast agents and a rare condition Research has revealed an association between the commonly used gadolinium-based MRI contrast agents and a rare disease called nephrogenic systemic fibrosis. The vast majority of the cases have...
BREAKTHROUGHMEDIA
Confocal microscopy The Atlas of Confocal Laser Scanning In-Vivo Microscopy in Ophthalmology discusses the principles of confocal in vivo microscopy, including slit-scanning techniques, the basics of image formation and...
Live-cell imaging Two protocols for visualizing live cells are accessible in the January issue (Volume 2, Issue 1) of the online database Cold Spring Harbor Protocols, produced by Cold Spring Harbor Laboratory Press...
Bionanotechnology The 298-page volume Biomolecular Computation for Bionanotechnology details the tools, methods and issues that are driving research in nonsilicon computing technology. It discusses the process of...
Laser safety The “2007 Laser Safety Training Catalog” from Laser Institute of America provides an overview of the organization’s local and online course offerings. Available in print and in pdf, the 18-page...
Research products The “2007 Life Science Catalog” from Promega Corp. details items for amplification, genetic identity, microarray analysis, in vitro transcription, molecular diagnostics, DNA and RNA purification,...
Labels, conjugates Available from Evident Technologies Inc., the “Life Sciences Catalog V9” details quantum dot fluorescent labels and conjugates for research in the life sciences. The first part of the 24-page...
Laboratory guide An addition to the Experimenter Series, the fourth edition of Molecular Biology and Genomics includes sections on minisequencing, pyrosequencing and RNA-interference, as well as a brief introduction...
Assay technology The second edition of the report “Assay Development and Technologies” from Research and Markets Ltd. provides an assessment of the capabilities, strengths, weaknesses and expectations of assays and...
Multidetector CT The volume Atlas of Non-Invasive Coronary Angiography by Multidetector Computed Tomography presents more than 160 illustrations — 116 of them in color — depicting the capacity of the technique to...
IR fluorescent reagents The “Infrared Fluorescent Products and Applications Guide” from Li-Cor Biosciences presents an expansion of reagent products, including the IRDye infrared dye secondary antibodies and conjugates,...
POST SCRIPTS
Close observation reveals unexpected player in coral reef recovery Coral reefs comprise arguably some of the most diverse, fragile and beautiful ecosystems on the planet. Their structure, composed mainly of calcium carbonate secreted by living coral polyps, provides shelter for fish and marine invertebrates and helps protect nearby shorelines from erosion. Their critical role, however, cannot save them from destruction — other less hospitable ecosystems are...
PRODUCTS
Filter sets With the addition of 15 filter sets for as many fluorescent proteins, Omega Optical Inc. now offers filter sets for a total of 35 proteins. Providing a high signal-to-noise ratio for low-light-level live-cell imaging experiments, the sets are manufactured using the proprietary Alpha technology, which produces steep slopes and accurate band placement for maximizing excitation and emission energy....
Omega Optical LLC
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DPSS lasers Cobolt AB has released higher-power models of its Cobolt Calypso CW diode-pumped solid-state lasers. They are suitable for applications including cell sorting, high-throughput bioanalysis, and...
Cobolt AB
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Fluorescence filters JDSU now provides custom fluorescence filters for biomedical applications such as fluorescence microscopy, flow cytometry, microarray scanning, microplate reading, high-content screening and...
Lumentum Operations LLC
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Confocal Raman microscopy Princeton Instruments/Acton has launched its TriVista confocal Raman microscopy system. The triple spectrograph detects minute structural changes with resolution up to 0.13 cm–1 and low-frequency...
Teledyne Princeton Instruments
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Imaging software Siemens Medical Solutions Inc. has updated its Radiology Information System software with the introduction of syngo Workflow 28.0 SLR. The medical imaging software is designed as an easy-to-learn...
Siemens Medical Solutions USA Inc.
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Laser diodes Edmund Optics Inc. has introduced a line of laser diode modules for OEMs to integrate into medical or research equipment. The 10 models are modulated or unmodulated, have 635- or 785-nm beams,...
Edmund Optics Inc.
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UV spectrometer McPherson Inc. has released the 248/310, an ultraviolet and soft x-ray spectrometer. The instrument can detect wavelengths from ~1 to 300 nm and can measure laser harmonics from 4 eV to 1.2 keV. It...
McPHERSON
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Mass spectrometry Fleximaging 2.0 software from Bruker Daltonics Inc. enables acquisition and evaluation of Maldi-Tof and Tof/Tof data with its Flex mass spectrometers. Maldi imaging with the software enables...
Bruker Daltonics Inc.
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Small monitor The UNO from Gentec Electro-Optics Inc. is a power monitor that reads both thermal- and photodetectors. It has a 76 × 57-mm LCD display with 23-mm digits that are high in contrast, allowing them to...
Gentec Electro-Optics Inc.
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Streak camera The OptoScope SC Streak Camera from Optronis GmbH provides time-resolution measurements from milliseconds down to 2 ps. It features a 100-MHz Ethernet interface, synchroscan mode operation up to 250...
Optronis GmbH
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USB 2.0 cameras Measuring 44 × 44 × 56 mm, the Lm series CCD cameras are suitable for industrial and scientific applications involving space constraints and low-light conditions. Available from Lumenera Corp., they...
Teledyne Lumenera
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700-MB/s frame grabber Epix Inc. has released Pixci E4, a frame grabber for use with four-lane PCI Express buses. Featuring an advanced chip that has high-speed serial transceivers, made by Altera Corp., the card can...
EPIX Inc.
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LED light sources The Dragon series high-power LED light sources from Lightspeed Technologies provide narrow- or broadband output in a wide-field or focused beam. The flexible system of interchangeable components...
Lightspeed Technologies Inc.
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Fiber light source Intensilight, a mercury-fiber light source, never requires alignment and provides stable, flicker-free illumination for epifluorescence research. Produced by Nikon Instruments Inc., the device has a...
Nikon Instruments Inc.
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Filter wheel For optical microscopes, Tofra Inc. has released a filter wheel with an integrated controller that saves space. The wheel is compact, measuring 17 mm thick with a maximum package dimension of 180 mm....
Tofra Inc.
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Lifetime measurement PicoQuant has introduced the PHR 800, a router that enables connection of up to four PicoHarp photon-counting systems. With the interconnected systems, users can simultaneously measure fluorescence...
PicoQuant GmbH
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Diode laser Alfalight Inc. has introduced a diode laser that provides 6 W of 976 ±4-nm output into a 105-μm, 0.15-numerical-aperture fiber. Its compact, hermetic six-pin package meets the Telcordia GR-468...
Alfalight Inc.
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Deformable mirror An enhanced deformable mirror from Boston Micromachines Corp. improves the performance of retinal imaging systems, enabling earlier detection of eye diseases such as glaucoma, diabetic retinopathy...
Boston Micromachines Corp.
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Optical trap detectors Large-aperture, multireflection optical trap detectors are available from Spectrum Detector Inc. Based on National Institute of Standards and Technology traceable calibration-transfer standards, the...
Gentec-EO USA Inc.
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Near-IR Camera XenICs has introduced the Cheetah near-IR digital camera, which is available in models that have frame rates of 60, 400 or 1750 Hz. Utilizing an InGaAs detector that provides 640 × 512-pixel...
Xenics
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Diode lasers A line of high-brightness, single-emitter diode lasers in the 650- to 690-nm range has been announced by nLight Corp. The devices rely on proprietary nXLT technology and are available in either...
nLIGHT Inc.
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BIOPHOTONICS 2007
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