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BioPhotonics - Jan/Feb 2023


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Features
Advanced Holography Efficiently Illuminates Neuronal Patterns Demystifying the complexity of the human brain is one of the last frontiers in diagnostics and therapeutics. When the brain is sufficiently understood by clinicians, the benefits for human well-being...
Top Hat Illumination Provides Even Light Distribution Across Samples Even illumination patterns are of great importance when applied to biomedical imaging because they prevent lighting artifacts that could distort the picture of the sample being analyzed. Therefore,...
Optical Photothermal IR Spectroscopy Targets Single-Cell Metabolomics Due to its unique molecular fingerprinting capability, infrared spectroscopy has been widely used to interrogate the overall biochemistry of biological systems. Over the years, this capability has...
Acousto-Optic Components Overcome Limitations in Confocal Microscopy Confocal and multiphoton microscopy are commonly used to provide 3D-resolved images of in vitro or in vivo tissue samples without physical sectioning. But there are also inherent trade-offs in the...
Editorial
The mission continues With the launch of BioPhotonics in the fall of 1994, its publishers set out to create what no other magazine had done before: a forum for in-depth reporting on photonics solutions for the medical and biotechnology disciplines. The magazine would become a resource for physicians, researchers, and technicians who wished to learn more about such solutions in the areas of diagnostics, analytics, and...
Show Preview
2023 Prism Awards to Showcase Commercial Innovation in the Photonics Cutting-edge technologies from both emerging startups and longtime industry stalwarts are among this year’s finalists for the SPIE Prism Awards. The 24 companies and their innovations, across eight categories, will be honored the evening of Feb. 1 during a gala banquet at SPIE Photonics West. The annual event, which recognizes industrial innovation in photonics, will celebrate its 15th...
BioScan
Fluorophore Modified to Expand Monitoring of Cell Dynamics A genetically modified fluorescent protein has exhibited the shortest fluorescence emission wavelength to date, researchers at Osaka University reported. The fluorophore, named Sumire, emits 414-nm...
Multimodal Microscopy Provides Window into Viruses’ Beginnings To better understand how viruses breach the protective layers of cells that line the airways and gut, Duke University researchers used multimodal microscopy to capture real-time video footage of...
Light-Activated Molecular Motors Achieve Fluorescence In their study of rotary molecular motors, researchers in the laboratory of Ben Feringa at the University of Groningen have combined two light-mediated functions — motion and fluorescence...
Pump Laser Modules Show Promise for Ophthalmologic Treatments Researchers at the Berlin-based Ferdinand-Braun-Institut (FBH) developed a pump laser module for ophthalmologic treatments. The module offers a cost-effective pump source for laser systems that are...
NIH Grant Supports Portable OCT Detection of Jaundice in Newborns A smartphone-based system that relies on OCT to detect jaundice in newborns will be put to use diagnosing very young patients in the U.S. and Nigeria, thanks to a nearly $500,000 grant from the...
Optical Interfaces Could Stimulate Nerve-driven Activity Engineers at the University of New South Wales (UNSW Sydney) demonstrated an approach to measure neural activity using light. The team’s optical sensors, called optrodes, achieved accurately...
Scientists Collaborate to Create Biomedical Imaging Center Researchers from the University of Illinois Urbana-Champaign will use funding from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) at the National Institutes of Health (NIH)...
Nobel Prize-Winning Techniques Help Resolve Imaging Challenge Using a technique that was recently awarded the 2022 Nobel Prize in chemistry, researchers at Cornell University used expansion microscopy to study lipids, the water-repellent, dynamic components...
Optica Elects 2023 Vice President, Directors-at-large The membership of Optica elected James Kafka as the society’s 2023 vice president; Kafka is CTO at Spectra-Physics and an MKS fellow. Julie Sheridan Eng, CTO at Coherent Corp., and Ulrike...
Laser Surface Modification Aims to Reduce Infection from Implants To help prevent infections caused by orthopedic implants, Purdue University researchers developed a laser-assisted surface modification process that may improve the efficacy of the implanted device....
Superresolution Method Could Improve Understanding of Gene Function An interdisciplinary team from the Centre for Genomic Regulation (CRG) and the Institute for Research in Biomedicine (IRB Barcelona) has developed an imaging technique that captures the structure of...
Startup to Shrink Miles-long Plasma Accelerators to Room Size Austin, Texas-based TAU Systems raised $15 million in seed investment that the company will use to develop compact particle accelerator technology. According to the company, the laser-driven particle...
3 Questions
3 Questions with Wouter Charle BioPhotonics spoke with Wouter Charle, program manager for hyperspectral imaging technology at imec, who leads off-the-shelf and evaluation system activities. After starting his career in 3D machine vision, Charle joined imec in 2014 to help grow the hyperspectral imaging business. He discusses how placing hyperspectral filters directly on a normal image sensor developed by imec allows for the...
BioOpinion
Portable photodynamic therapy could take cancer treatment worldwide Mortality from cancer is on the rise in low- and middle-income countries, and the need is urgent for requisite treatment modalities that are low-cost, portable, and versatile in clinical environments with limited resources. One technique that may help fill this need is photodynamic therapy (PDT), which uses tumor-localizing photosensitizing agents (photosensitizers) to deliver light to the target...
Postscripts
Putting ‘skin in the game’ to restore vision A team of scientists at Link?ping University and LinkoCare Life Sciences in Sweden may have found an answer to the problem of restoring people’s eyesight — and it’s only skin deep. Porcine skin, that is. The human cornea is composed primarily of collagen. If an effective way could be found to transplant this material from another source, such as from the skin of humans or...
Products
Diode Laser The LBX-488 LaserBoxx diode laser from Oxxius SA provides a low-noise optical output, ultrahigh beam quality, and fast modulation. The system consists of a laser diode emitter with an...
Oxxius SA
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sCMOS Camera The ZL41 Cell sCMOS camera from Andor Technology is designed for life science researchers. The ZL41 Cell transforms a normal fluorescence microscope into a super-resolution microscope using...
Andor Technology
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Zinc Selenide Optics High-quality zinc selenide (ZnSe) lenses, output couplers, and mirrors from Laser Research Optics are optimized at 1.06 μm for medical laser OEMs. The devices are manufactured to...
Laser Research Optics
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Video Borescope Cameras The SV-2000 video borescope camera from Canon Medical Systems USA Inc. is a chip-on-tip device for inspection applications in compact spaces. Two camera control unit options, both with...
CANON MEDICAL COMPONENTS U.S.A., Video Sensing Devices
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Image Stabilization Camera The FCB-EV9520L camera from Sony Corp. is a 1/2.8-in. device with high sensitivity and image stabilization. The 2-MP STARVIS 2 image sensor provides the device with enhancements within the NIR...
Sony Corp.
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Violet Laser Diodes The HL40173MG and HL40175MG laser diodes from Ushio are 600-mW electrostatic discharge-resistant violet devices. The devices maintain PIN layout compatibility with conventional products while...
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Retinal Camera The NW500 Non-Mydriatic Retinal Camera from Topcon Corp. is a fully automatic, non-mydriatic system that delivers reliable, sharp-quality imaging with enhanced capability. The camera offers...
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Semiconductor Laser Diode The Metal Can PLT5 522FA_P-M12 from ams-OSRAM AG is an off-the-shelf semiconductor laser emitter with a 514-nm wavelength output required by many life science, R&D, and diagnostics applications....
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SWIR Camera The pco.pixelfly™ 1.3 SWIR camera from Excelitas Technologies Corp. is a high-performance machine vision camera with an InGaAs image sensor. With a sensor that is IMX990-sensitive in the...
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Digital Microscope FRONT digital microscopes from TAGARNO provide high stability at 600× magnification. The system’s design reduces camera movements caused by someone walking past the microscope...
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Laser Diode Gel Illuminator The Gel-Bright™ Laser Diode Gel Illuminator from Biotium Inc. features laser diode-based illumination technology for a wide selection of fluorescent dyes without requiring laser safety glasses....
Biotium Inc.
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NIR Quantum Dots CD Bioparticles’ NIR Quantum Dots for biomedical imaging feature fluorescence intensity and stability, electron density, and strong tissue penetration ability. The dots can be used in...
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