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DIGITAL EDITION
FEATURES
Research, Innovation Lead SPIE BiOS 2019
SPIE’s BiOS conference and exhibition is renowned worldwide as one of the most important events in the biophotonics industry. It brings together researchers, professors, students, companies,...
PDT, Customized Protocols Team Up for Enhanced Clinical Translation
Photodynamic therapy is a powerful technique in the local, selective treatment of cancer and infectious diseases, but customized optical device protocols must be added to the mix for major clinical...
Advancements in Raman Spectroscopy Find Real-World Uses in the Life Sciences
Since its development in the mid-1920s, Raman spectroscopy has been used to study various low-frequency vibrational modes in molecular systems. In contrast to its counterpart — Fourier...
Molecular Imaging Emerges as a Cancer Surgery Tool
Molecular imaging has become an invaluable tool in cancer treatment. Single-photon emission computed tomography (SPECT) and positron emission tomography (PET) are entering routine clinical use for...
Prism Award Finalists Vie for 2019 Honors
The Prism Awards for Photonics Innovation bring anticipation and excitement each year to the Photonics West exhibition in San Francisco. Renowned as the “Oscars of the photonics...
Member Exclusive
Wearable Sensors Challenge Traditional Medical Technology
From Apple to Fitbit to Garmin to Google, in the U.S. alone, dozens of companies are producing wearable sensors that record our movements as well as basic health information. Many of these devices...
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EDITORIAL
Wearable sensors save lives
With mass casualties, it can be easy for first responders to become overwhelmed amid chaos by the number of victims who need care. Quick action saves lives. Monitoring victims is vital and can make all the difference between lives saved and those lost. Researchers at the U.S. Department of Energy’s Pacific Northwest National Laboratory and the Responder Technology Alliance have stepped up...
BIOSCAN
Flexible Waveguides Exhibit Low Light Loss for Biosensors, Wearables
Tiny, flexible waveguides, made in a clear silicone commonly used for biomedical applications, were created by a research team at École Fédérale de Lausanne (EPFL). To create the waveguides, the team used multiphoton laser direct writing, a microfabrication method in which a light-sensitive chemical is polymerized with a focused laser to create finely detailed 3D structures.
Leibniz Institute Observes Neuronal Structures with Holography
Using a multimode optical fiber as thin as a human hair, scientists at the Leibniz-Institute of Photonic Technology have observed at high resolution the neuronal structures inside deep brain areas of...
Photocatalyst Used to Create a Safe, Sustainable Building Block for New Drugs
While searching for ways to use visible light to drive chemical reactions, a University of Michigan team found that by using photocatalysis, they could create a safe, inexpensive alternative to...
Optogenetics Drives Structural Changes in Embryo Tissue Development
Scientists at the European Molecular Biology Laboratory (EMBL) used optogenetics to drive structural changes in tissue development in Drosophila (fruit fly) embryos. Their experimental results showed...
Quantum Dots Replace Dyes to Stabilize Cell Imaging
A new molecular probe, based on the fluorescence in situ hybridization (FISH) technique, uses quantum dots (QDs) instead of fluorescent dyes to illuminate molecules and diseased cells. Developed by a...
OCTA Could Help Detect Early-Stage Alzheimer's
Researchers at Duke University used optical coherence tomography angiography (OCTA), a noninvasive imaging technique, to show that the small blood vessels in the retina at the back of the eye are...
Optoelectronic Interface Uses Fiber Optic Channel to Stimulate Brain Neurons
Research into ways to restore brain function has led to the development of an optoelectronic interface that allows interaction between electronic neuron-like generators and living neurons in the...
NIR Spectroscopy Enables Accurate Evaluation of Osteoarthritis
An arthroscopic NIR spectroscopic probe, developed at the University of Eastern Finland, could be used to quantitatively assess the health of joint tissues, improving physicians’ ability to...
OCT Tool Explores How Sound Moves Through the Ear
A vibrational imaging tool based on optical coherence tomography (OCT) is providing new insight into how the ear receives and processes sound waves. Called OCT vibrography, the tool was built by a...
Microscope Images Mouse Embryo Development at the Cellular Level
Researchers at Howard Hughes Medical Institute’s Janelia Research Campus developed a new microscope using adaptive light-sheet microscopy techniques to capture mouse development at the...
Team Discovers Light-Driven Structural Changes in Biomolecules
Using various spectroscopic methods, researchers at Ruhr-Universität Bochum (RUB) and Philipps-Universität Marburg have gained new insights into how the light-sensitive part of the biomolecule...
RAPIDSCAN
Tohoku, Advantest Develop In Vivo Skin Imaging Technology
An R&D group led by Professor Yoshifumi Saijo of Tohoku University and Noriyuki Masuda of Advantest Europe GmbH has succeeded in developing in vivo skin imaging technology that can simultaneously generate dual-wavelength photoacoustic images and ultrasound images. As part of the “Innovative Visualization Technology to Lead to Creation of a New Growth Industry” project operated under Japan’s...
NIH Names Carnegie Mellon’s Zhao Top New Innovator
Yongxin (Leon) Zhao, assistant professor of biological sciences at Carnegie Mellon University, has received a National Institutes of Health (NIH) Director’s New Innovator Award. The award is part of...
FDA Approves Zeiss’ ReLEx SMILE
Zeiss’ medical technology segment has announced FDA pre-market approval (PMA) for its ReLEx SMILE system, expanding myopia treatment to patients with astigmatism. ReLEx SMILE utilizes the...
Luminate NY Initiative Welcomes Bio-Heavy Cohort II
New York state’s Luminate NY accelerator held its Lightning Awards at the Dryden Theatre at the George Eastman House in Rochester, going from 21 chosen competing companies to 10 finalists. The...
Moffitt’s Gillies Receives World Molecular Imaging Society’s Top Award
Robert Gillies, chair of the cancer physiology department and vice chair of radiology research at Moffitt Cancer Center, was awarded the 2018 Gold Medal Award by the World Molecular Imaging Society....
Revitalize Laser Care Opens Denver Facility
Laser skincare treatment provider Revitalize Laser Care has opened a tattoo removal clinic in Denver. Revitalize Laser Care uses state-of-the-art, three-wavelength laser machines imported from Italy...
Endocon Uses GE Laser Technology for Hip Implant Removal
Using General Electric’s Additive Concept Laser Direct Metal Laser Melting (DMLM) technology, medical device developer Endocon GmbH has developed a 3D-printed surgical tool to improve and simplify...
UC San Diego Launches Nikon Imaging Center
The Nikon Imaging Center, a collaborative microscopy center that provides local researchers with access to the latest imaging technologies, has opened at the University of California, San Diego. “UC...
STORM Pioneer Wins One of Six $3M Breakthrough Prizes
The Breakthrough Prize Foundation and its sponsors — Sergey Brin, Priscilla Chan and Mark Zuckerberg, Ma Huateng, Yuri and Julia Milner, and Anne Wojcicki — announced the recipients of...
UNL Uses Optomec AM System for Magnesium Medical Implants
The University of Nebraska-Lincoln (UNL) is using a LENS Hybrid Controlled Atmosphere System from additive manufacturing systems supplier Optomec to develop dissolvable magnesium components that will...
Nanoscope Technologies Receives Major NIH Research Grant
Nanoscope Technologies was awarded a bioengineering research grant by the National Institute of Health (NIH) to advance bioluminescent Multi-Characteristic Opsin (MCO) for the simultaneous optical...
BIOPINION
Examining sex-based differences in the brain
It may seem obvious, but biological males differ significantly from biological females in many aspects of physiology and behavior. These differences have profound implications for the treatment and prevention of diseases such as cardiovascular disease, asthma, renal failure, cancer, and diabetes — implications long overlooked, but gaining currency perhaps due to the increasing number of...
POSTSCRIPTS
Predicting rogue behavior
On the afternoon of Nov. 9, 1975, the sturdy and storied freighter SS Edmund Fitzgerald, well known in the Great Lakes region for its record-breaking hauls of iron ore, set out across eastern Lake Superior, carrying a full cargo destined for a Detroit steel mill. En route, it joined a second freighter, the SS Arthur M. Anderson, and by late afternoon of the following day, the two ships were...
PRODUCTS
Optical Filters
VIS Blocking LWP Filters from Optical Filter Source LLC are designed for SWIR through MWIR wavelengths. Originally developed for research science, the filters provide <OD5 blocking from...
Optical Filter Source LLC
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Telecentric Lenses
TECHSPEC MercuryTL Liquid Lens Telecentric Lenses from Edmund Optics Inc. are ideal for gauging, measurement, and placement applications requiring quick depth-of-field adjustment. The devices...
Edmund Optics Inc.
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Spectrophotometer
The Cary 3500 UV-VIS system from Agilent Technologies Inc. is a spectrophotometer designed to help life science, pharmaceutical, and biopharmaceutical research communities simplify their analyses,...
Agilent Technologies Inc., Chemical Analysis
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Linear Cameras
Manx linear cameras from Xenics NV are high-performance SWIR cameras that provide high-speed and quality line-scan imaging. Manx cameras are offered in three different resolutions: 512, 1024,...
Xenics
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Traction Drives
The MAR-17-2-2.1 and MAR-23-2-2.1 Traction Drives from Rolling Motion Industries are two-way, gearless traction drives with only six moving parts. The devices use an engineered traction fluid...
Rolling Motion Industries
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Advanced Flow Cytometry System
The Northern Lights series of advanced flow cytometry systems from Cytek Biosciences Inc. provides three lasers and more than 24 colors at a price point typically attached to systems with far fewer...
Cytek Biosciences Inc.
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THz Time-Domain Spectrometer
The Newport Terahertz Time-Domain Spectrometer (THz-TDS) from MKS Instruments Inc. is designed for the scientific research market. The THz-TDS is designed to work with amplified, femtosecond...
MKS Instruments Inc.
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Particle Measurement Software
The updated Particle Solutions software suite from Testa Analytical Solutions eK integrates characterization of the DLS, SLS, Phase Analysis Light Scattering (PALS), Micro-Rheology, and Size...
Testa Analytical Solutions eK
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Microtiter Plate
The µ-Plate 384 Well Clear from ibidi GmbH Is a novel microtiter plate that combines automated cell cultivation with high-resolution microscopy. The flat, thin polymer coverslip bottom...
ibidi GmbH
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Fluorescence Imaging Technology
NIR/ICG Fluorescence Imaging technology from KARL STORZ Endoscopy America Inc. is an FDA-cleared ICG technology for endoscopic neurosurgery in a 4-mm format. The NIR/ICG Imaging System assists...
Karl Storz Endoscopy-America Inc.
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Snapshot Sensor
The Gocator 3504 Smart 3D Snapshot Sensor from LMI Technologies Inc. features 6-µm XY resolution. With +/−0.5-µm measurement repeatability, the device provides robust inline...
LMI Technologies Inc.
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Optical Microscope
The HT-1 novel optical microscope from Tomocube Inc. utilizes diffraction tomography to generate 3D holographic images of unlabelled live cells. At the heart of the HT-1 is a complex digital...
Tomocube Inc.
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Global Shutter Image Sensors
The OG02B1B, OG02B10, and OV9285 global shutter image sensors from OmniVision Technologies Inc. are designed to be cost-effective solutions for a wide range of consumer and industrial machine vision...
OmniVision Technologies Inc.
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XY Stage
The AU200-170x170 stage from Optimal Engineering Systems Inc. is a low-profile device measuring 108 mm high with a compact footprint of 458.5 × 458.5 mm. The linear travel of the X and Y...
Optimal Engineering Systems Inc.
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