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DIGITAL EDITION
FEATURES
OCT Presents Multidimensional Imaging for Diagnosis and Detection
Optical coherence tomography (OCT) is a noninvasive imaging technique that is used to deliver high-resolution images in two or three dimensions. It relies on the wave-like properties of light to...
Liquid Crystal Sensors Provide Rapid COVID-19 Diagnosis
The global outbreak of COVID-19 has prompted scientists worldwide to focus their research on the virus over the last year, particularly those who work with optical and sensing technologies. Some have...
Charge Clusters in a Monomeric Protein Alter Optical Absorption
Electronic absorption of proteins that lack cofactors, prosthetic groups, or noncoded amino acids as part of their structure has traditionally been thought to originate from protein backbone (peptide...
Quantum Cascade Lasers Boost Life Science Research
Over 20 years have passed since the first quantum cascade laser (QCL) sources were commercialized. QCLs that operate at room temperature using thermoelectric cooling are now ubiquitous. These lasers...
EDITORIAL
Proteins make the invisible visible
Changes in the proteins inside a cell may indicate the presence of a particular disease or condition, and these changes have been historically difficult to track. For many years, it was believed that light in the visible range (>320 nm) was not absorbed by proteins, but recent research has shown that this is not the case. Invasive techniques of investigation, such as the injection of...
BIOSCAN
Fluorescence Microscopy Technique Images Brain at High Resolution
A noninvasive brain imaging technique developed by researchers at ETH Zurich and the University of Zurich works in the near-infrared (NIR) spectrum to enable superresolution deep-tissue fluorescence microscopy at four times the depth limit imposed by light diffusion. According to the researchers, the technique, called diffuse optical localization imaging (DOLI), operates in a resolution-depth...
AI-driven Method Developed to Diagnose Neurodegenerative Diseases
A combination of OCT, adaptive optics, and neural networks has the potential to enable better diagnosis and monitoring for eye and brain diseases, such as glaucoma, that damage neurons. The...
Programmable 2D Nanomaterial Captures Artificial Light for Bioimaging
A light-harvesting nanomaterial inspired by the hierarchically structured biominerals in nature could be used to build artificial light-harvesting systems for bioimaging, photovoltaics, and other...
CELLINK Acquires Nanoscribe, Visikol
The CELLINK Group, a bioconvergence company focused on the application areas of bioprinting, multiomics, cell line development, and diagnostics, strengthened its position in the biophotonics space...
Organic Optogenetics Tool Shines Light on Brain Communication
Light-sensing proteins called rhodopsins are used in optogenetics to control neuronal activity, but existing rhodopsins can have low efficacy, especially when they are used to control synaptic...
Modified Antibodies Boost Photodynamic Therapy’s Efficacy
Adding antibodies to photodynamic therapies can bolster their efficacy, according to research conducted by Texas A&M University and the University of São Paulo. The work reviewed the...
Ultralow-Loss Mirrors Boost Spectroscopy, Detection
Collaborators from industry and academia have demonstrated high-performance laser mirrors in the mid-infrared range that absorb fewer than 10 out of a million photons. The achievement, enabled by...
Virginia Tech Receives $2.4M to Optically Measure Brain Activity
Researchers at the Fralin Biomedical Research Institute at Virginia Tech Carilion School of Medicine (VTCSM) received a $2.4 million National Institutes of Health grant to use optically pumped...
Zapata Valencia Awarded 2021 Teddi C. Laurin Scholarship
Samuel Ignacio Zapata-Valencia has been awarded the 2021 Teddi C. Laurin Scholarship for his contributions to the field of optics and photonics. Zapata-Valencia, a master’s student at...
Interferometry Enables Measurement of Brain Blood Flow, Activity
A spectroscopy technique developed at the University of California, Davis (UC Davis) is able to noninvasively measure brain blood flow and activity. The method, called functional interferometric...
Light-Controlled Nanoparticles Support Noninvasive Nanomedicine
Scientists from ITMO University have developed a production method for bio-integrated optical nanomaterials based on Mie-resonant silicon nanoparticles. The nanoparticles used in the work are covered...
Hybrid Microscopy Method, AI Deliver Robust Images in Seconds
Scientists at the European Molecular Biology Laboratory (EMBL) combined AI algorithms with light-field microscopy and light-sheet microscopy. The hybrid, AI-enhanced approach shortened the time...
Eikon Therapeutics Closes $148M Financing Round, Names CEO
Drug discovery and development company Eikon Therapeutics closed $148 million Series A financing and appointed Roger Perlmutter CEO. Eikon’s drug discovery platform uses superresolution...
Terahertz Optoacoustic Method Images Water-Rich Samples
A research team led by Zhen Tian and Jiao Li at Tianjin University developed a method for analyzing water-rich samples using time-domain terahertz (THz) optoacoustics. The method overcomes a...
Light-Activated Molecule Eliminates Alzheimer’s Protein in Live Mice
Research from the University of Tokyo has demonstrated the efficacy of a small, light-activated molecule in removing clumps of amyloid protein found in the brains of mice with Alzheimer’s...
Tissue-Integrated Microlasers Measure Beating Heart of Zebra Fish
An imaging method developed by researchers at the University of St. Andrews aims to overcome difficulties in analyzing and imaging the beating heart. Researchers integrated tiny lasers into heart...
ZEISS Completes Innovation Center, HQ of US Medical Technology Business
ZEISS completed construction on a $180 million R&D, production, sales, and customer service facility in Dublin, Calif., in the San Francisco Bay Area. The ZEISS Innovation Center supports...
BIOPINION
Flow cytometry standards are needed to ensure effective diagnosis and treatment
Flow cytometry is an incredibly powerful technique that has been used for decades to measure the physical and chemical characteristics of populations of cells, constituents of cells, and other small particles of biological and nonbiological origin. As the uses of this technology have expanded, so too has the need for standardization in measurement parameters. In flow cytometry, particles flow in...
POSTSCRIPTS
Lasers deter birds from salmon run
Juvenile salmon traveling in the Columbia River near McNary Dam in Oregon are vulnerable to hungry birds that lurk overhead. Thanks to the Walla Walla District of the Army Corps of Engineers, which deployed lasers in the area, the endangered fish are now protected from above as well as in the water. McNary Dam, maintained by the Corps, stretches 1.4 miles and spans the Columbia River between...
PRODUCTS
Raman Analyzer
The Virsa™ Raman analyzer from Renishaw PLC features WiRE™ 5.5 software, enabling its users to analyze samples outside of the confines of the laboratory microscope using remote fiber...
Renishaw PLC, Spectroscopy Products Div.
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Biocompatible Photoresin
Bio-compatible IP-PDMS photoresin from Nanoscribe GmbH is designed for the 3D microfabrication of elastomer-based applications, microsystems, and devices. The printing material is soft, highly...
Nanoscribe GmbH & Co. KG
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Virus Detection System
An optical DNA rapid detection system from OZ Optics Ltd. can detect COVID-19 and other viruses in individuals. The system is designed to detect fluorescence and color changes from dyes that...
OZ Optics Limited
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Hyperspectral Microscope
The IMA hyperspectral microscope from Photon etc. Inc. has been announced by SphereOptics GmbH. The microscope delivers spectral and spatial information in the VIS, NIR, and SWIR wavelength...
SphereOptics GmbH
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Automated Cell Counter
The CytoSMART Exact FL automated cell counter from CytoSMART Technologies is a dual fluorescence device with an expanded field of view and high performance. The system features an advanced...
CytoSMART Technologies
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Microscopy Flow Chamber
The µ-Slide Spheroid Perfusion flow chamber from ibidi GmbH is ideal for the long-term culture and high-end microscopy of 3D cell aggregates such as spheroids, organoids, or tissue. The...
ibidi GmbH
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Petrographic Digitization System
The Axioscan 7 petrographic digitization system from ZEISS is designed for virtual microscopy, collaboration, and machine learning data analytics. The system expands the possibilities of...
Spectrophotometer Software
The EasyApps® Secure, a 21 Code of Federal Regulations Part 11 compliance-ready software option for the DS-11 series range of microvolume spectrophotometers and fluorometers has been announced by...
DeNovix Inc.
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Spectrophotometer
CRAIC Technologies’ 508 PV™ UV-visible-NIR spectrophotometer is designed to be added to an open photoport of a microscope or probe station so that you can nondestructively analyze the...
CRAIC Technologies
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Glass-Bottom Microplate
The Krystal™ Glass Bottom microplate from Porvair Sciences Ltd. is designed for whole-plate CCD imaging and laser detection applications. The device combines the optical properties of...
Porvair Sciences Ltd.
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Sample Heating Device
The ionRocket from BioChromato Inc. is a temperature-heating device for direct thermal desorption and pyrolysis of samples prior to ionization and analysis by mass spectrometry. The system...
BioChromato Inc.
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Medical Image Sensor
The OH0TA OVMed® medical image sensor from OmniVision Technologies Inc. is designed to improve image quality and reduce power consumption for endoscope and catheter cameras while helping surgeons...
OmniVision Technologies Inc.
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