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BioPhotonics: July 2007

BioPhotonics
 July 2007


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FEATURES
High-Content-Screen Microscopy Enables Large-Scale Multiplex Image Analysis Quantitative analysis of cellular images is critical for investigating neuronal function and disease mechanisms in modern neuroscience drug discovery research. In the study of Alzheimer’s disease, neurotoxicity of β-amyloid peptide 1-42 (Aβ1-42) has been a primary focus of research for the past decade. Although β-amyloid has long been known to play a central role in Alzheimer’s...
Flexible Image Analysis Historically, biology researchers examined samples predominantly by eye, but now digital capture of images is commonplace, and objective quantification of those images using automatic analysis...
Spotting Prostate Cancer Automatically Prostate cancer, according to the American Cancer Society, is among the most common malignancies in men and is the second leading cause of death, accounting for about 10 percent of male...
Automation of Whole Slide and Tissue Microarray Interpretation Digital techniques have taken center stage in clinical medicine as well as in biomedical research. Digital telemedicine, radiology and cardiology have replaced traditional subjective diagnostic...
Nanotechnology for Biology: Exploring Cellular Activity and Abnormality Nanotechnology is becoming increasingly popular in the medical field, both in imaging and in direct treatment applications. The risks associated with nanotechnology are prompting researchers and...
Medical Laser Market on the Rise Minimally invasive laser surgery is growing in use and is preferred for many procedures because lasers can reach areas where access is difficult with traditional surgical methods. The technique...
Compact High-Power Diode Lasers in Dental Surgery For about 10 years, diode lasers have been established medical devices. They are powerful tools for surgery and for dental applications such as endodontics and paradontics because they work quickly,...
CO2 Laser Used in Minimally Invasive Laryngeal Surgery The CO2 laser has long been a therapeutic workhorse in hospitals and physicians’ offices. It is suited for surgical applications, including precise incision and excision procedures, as well as for...
Holmium:YAG Laser in Clinical Urology The holmium:YAG laser is widely used in urologic surgery. The solid-state laser is available in variable power configurations from 10 to 100 W and is released in a pulsed-mode system, allowing...
AS WE GO TO PRESS
DNA-encapsulated silver nanoclusters offer IR emission without blinking Although there are many types of fluorophores available for biological studies, single-molecule studies and in vivo imaging still can be challenging with today’s options. Fluorophores based on...
FISH-ing for cancer just got easier Fluorescence in situ hybridization (FISH) can detect chromosomal mutations that cause cancer, but the technique can take days to perform and cost hundreds of dollars. Consequently, the method is not...
BREAKTHROUGHMEDIA
Photonic devices The 23-page brochure “2007 Photonic Devices: Electron Tube Devices and Applied Products” has been released by Hamamatsu Photonics KK, Electron Tube Div. The full-color publication details...
Biophoton emission The volume Biophotonics and Coherent Systems in Biology consists of original papers presented at the Third Alexander Gurwitsch Conference on Biophotonics and Coherent Systems in Biology, Biophysics...
Vibration isolation The “2007 General Catalog” from Technical Manufacturing Corp. details the company’s vibration isolation products and their applications. The 124-page guide features the Stacis 2100 active...
Laser-safe eyewear Laservision•USA (formerly Trinity Technologies) has released a 19-page capabilities brochure that features laser protective technologies compliant with the ANSI Standards for the Safe Use of...
Fourier optics Part of the Wiley Series in Pure and Applied Optics, the book Diffraction, Fourier Optics and Imaging presents theories of diffraction, imaging and related topics based on Fourier analysis and...
Fluorescence directory Who’s Who in Fluorescence 2007 publishes the names and contact details of scientists who employ fluorescence methodology and instrumentation in their work, as well as related specialty keywords,...
Research products The “Research Products Catalog 2007” from Cambrex, now a part of Lonza, details items for cell biology, bioassays, cell culture, molecular biology and endotoxin detection. It specifies bioassay kits,...
Tissue optics Covering the area of tissue optics, the textbook Biomedical Optics: Principles and Images is based on lecture notes for a graduate course in bio-optical imaging that was taught by the authors. The...
Laser safety standards The Laser Institute of America (LIA) has released a revised edition of the American National Standard for Safe Use of Lasers (ANSI Z136.1). New guidelines have been incorporated into the 2007 edition...
FO spectroscopy A supplier of instruments for fiber optic spectroscopy, including spectrometers, light sources, fiber optic cables and probes, and accessories, Avantes BV has released its “Catalog 2007-2008.” The...
POST SCRIPTS
Nearly Forgotten Links to Alois Alzheimer One hundred years ago, Alois Alzheimer used a simple light microscope to examine brain samples from a 51-year-old female who had died after a long battle with dementia. Through the observations, conducted during his time at the Königliche Psychiatrische Klinik in Munich, Germany, he identified structures characteristic of the patient’s condition, which fellow physician Emil Kräpelin named after...
PRODUCTS
Scanning probe microscope Veeco Instruments Inc. has unveiled the Innova scanning probe microscope, which can be used for life sciences applications. The device offers low noise, closed-loop scanning, quick and easy tip and sample exchange, and top-down optics with better than 1-μm resolution. The optics ensure precise probe positioning on the sample and are completely contained within the protective instrument...
Veeco Instruments Inc.
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Cell cultivation In cooperation with the research center Jülich, ibidi GmbH has launched the μ-Slides elastic supported surfaces, which provide a soft surface for in vivolike cell cultivation. They allow the...
ibidi GmbH
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Laser diodes A line of laser diodes in the 730- to 750-nm wavelength range has been introduced by Frankfurt Laser Co. The Fabry-Perot single spatial mode laser diodes are available from 5 to 30 mW. They are...
Frankfurt Laser Company
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Laser series The BWF-5 laser series, employing diode/diode-pumped solid-state laser technology, has been announced by B&W Tek Inc. Standard wavelengths are available at 810, 940, 980 and 1080 nm, with output...
B&W Tek LLC
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Stereomicroscopes Models in the E-Zoom series stereo zoom microscopes from Edmund Optics Inc. provide either a 4:3:1 zoom ratio with 0.7× to 3.0× magnification or 6:3:1 zoom ratio with 0.8× to 5.0× magnification, and...
Edmund Optics Inc.
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Assay kit Molecular Devices has launched its live-cell Neurotransmitter Transporter Uptake Assay Kit, a homogeneous, fluorescence-based high-throughput screening procedure that requires no radioactive tags or...
Molecular Devices LLC
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Microplate washer BioTek Instruments Inc. has expanded its microplate washing product line with the ELx50 filter microplate washer. Based on the company’s automated eight-channel ELx50 strip washer, the new model has...
BioTek Instruments Inc.
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Video capture card The Matrox Vio Analog single-platform capture card from Matrox Imaging provides low-latency video output, supports 20-bit video, allows graphics overlay composition and automatically detects the...
Matrox Imaging
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Multilabel plate reader PerkinElmer Inc. has announced the TRF laser detection module for its EnVision multilabel plate reader. The module is a compact nitrogen laser unit designed to improve performance for time-resolved...
PerkinElmer Instruments
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Infrared camera Flir Systems Inc. has introduced the ThermoVision SC8000 MWIR camera. The device, with a 1024 × 1024-pixel InSb focal plane array, has a 16-channel readout, providing data at 205 megapixels per...
Teledyne FLIR Systems Inc.
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GigE camera The TM-2040GE GigE camera from JAI Inc. has 1600 × 1200-pixel UXGA resolution and software-selectable operation that allows users to choose between dual-tap mode at 34 fps with automatic channel...
JAI Inc.
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Galvanometer control The iDrive digital galvanometer scan head control from Scanlab AG operates via a closed loop between the galvanometer’s digital driver and the PC control board. The control enables simultaneous...
SCANLAB GmbH
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Beamsplitters Semrock Inc.’s RazorEdge Dichroic beamsplitters reflect a laser wavelength incident at 45° and efficiently pass a broadband of the longer Raman-shifted wavelengths. The ion-beam-sputtering-coated...
IDEX Health & Science - Semrock Optical Filters
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NIR-coated lenses The high-magnification Zoom 6000, 12× and Precise Eye lens systems from Navitar Inc. now are available with NIR coatings. The NIR systems — as with the non-NIR systems — allow zoom magnification from...
Navitar Inc.
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Piezo amplifier Released by piezosystem jena GmbH, the 12V40 CLE is a compact piezo amplifier with an integrated measurement system for low-voltage piezo actuators that is particularly suitable for OEMs. The...
piezosystem jena GmbH
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Plastic assay plates Porvair Sciences Ltd. offers clear polystyrene and opaque polypropylene 96- and 384-well plates for adsorption, mixing and storage applications, and for fluorescence, luminescence and scintillation...
Porvair Sciences Ltd.
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Stage inserts Prior Scientific Ltd. introduces its NZ100 and NZ200 NanoScan piezo focusing stage inserts, capable of creating images in the Z-axis with nanometer precision at 50 fps. With a maximum travel of 100...
Prior Scientific Inc.
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Digital camera kit The Infinity 1 digital camera kit for qualitative scientific imaging has been released by Media Cybernetics Inc. The kit includes a high-resolution CMOS color or monochrome microscopy camera that...
Media Cybernetics Inc.
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Light source The Colibri light source from Carl Zeiss MicroImaging GmbH uses high-performance LEDs for biomedical fluorescence research and routine fluorescence procedures. Ten wavelengths from the UV to dark red...
Carl Zeiss Spectroscopy GmbH
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Single-mode laser The XTL single-mode diode laser module from Toptica Photonics AG has applications in flow cytometry, display technology, photodynamic therapy, and high-content and high-throughput screening. It...
Toptica Photonics AG
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Laser energy sensors Suitable for multilaser laboratories and production facilities, the Multipurpose EnergyMax series laser energy sensors from Coherent Inc. offer wavelength coverage from 190 nm to 12 μm. The...
Coherent Inc.
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LED Microscope The DM1000 LED microscope released by Leica Microsystems GmbH incorporates a 4-W LED with a life-time of 100,000 h to provide color-neutral illumination, and a portable solar power supply is...
Leica Microsystems GmbH
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Digital microscope The Coolscope II system from Nikon Instruments Inc. incorporates a digital microscope, a digital camera and Web server capabilities. As with the original eyepieceless model, it can be operated via...
Nikon Instruments Inc.
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BIOPHOTONICS 2007
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