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BioPhotonics - March 2016
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Issue Library
Digital Edition
Features
Advances in Laser Diodes Can Bring Portability to Point-of-Care Photoacoustic Systems
Photoacoustic imaging (PAI) has attracted much attention in recent years as a complementary technique to classical ultrasound and optical coherence tomography. This novel technique combines pulsed...
Using Photonic Components to Design and Build Life Science and Analytical Instruments
Life science and analytical instruments based on optical techniques have moved from university and corporate research laboratories, through central diagnostic and pathology laboratories, to local...
Editorial
The Cavalry Is Coming
The doctor’s office has long served as the front line in the fight against disease and age-related ailments. Here, the undiagnosed threat is as dangerous as the undetected enemy. And in a scenario that would make most military generals queasy, the medical profession’s scouts — diagnostic technicians — commonly operate not in advance of the front, not at it, but behind it...
BioScan
NIR-Activated Nanoparticle Therapy Suppresses Tumors
A nanoparticle drug-delivery system that combines photodynamic and molecular therapies has been shown to suppress tumor progress and metastatic outgrowth in animal models. The complementary treatment could improve outcomes and mitigate toxicity for patients with pancreatic cancer and other treatment-resistant tumors. "A broad challenge in cancer treatment is that tumor cells use a network of...
Optogenetic Method Investigated for Neuron Repair
An optogenetics method has been used to stimulate the repair of a single neuronal circuit in zebrafish larvae. The method could have future therapeutic applications as a treatment for neuropathies in...
Worm Brain Imaging Illustrates Neurons' Role in Movement
A fluorescence microscopy technique has yielded 3D footage of brain activity in unrestrained worms, offering insight into how populations of neurons generate animal behavior. Researchers from...
Thermal Contrast Technique Reveals Cell Characteristics
A label-free technique based on a thermoelastic lens has been used to capture images of single cells with 2-μm resolution. The method could be used to perform histological analysis and for disease...
Fluorescence Imaging 'Video Pill' Made for Cancer Detection
A wireless capsule with fluorescence imaging capabilities could be swallowed by patients to aid in detection of cancers of the throat and gut. Previous versions of such "video-pills" have relied on...
No Differences Shown Between Supplimental LED, HPS Lighting in Tomato Quality
A feasibility study has shown that using LEDs as greenhouse grow-lights for tomato crops does not diminish fruit quality, suggesting a potential alternative for or supplement to high-pressure sodium...
Portable NIR Brain Imaging Device Offers Insight into Parksinsonian Syndromes
A portable near-infrared brain imaging device has been used to compare healthy brain activity and stability with that of people with Parkinsonian syndromes. The findings highlight the role of the...
Metal Labels Produce 3D Images of Neurons
Spectral confocal microscopy has been used to visualize neurons with the help of silver- and gold-based cell labeling. The development enables imaging of archived tissue samples, which could aid...
Diagnostic Method Employs Birefringence of Liquid Crystals
A detection system that uses birefringence as the sole optical output signal holds promise as a low-cost, rapid diagnostic tool for identifying biomarkers, viruses, bacteria and parasites in the...
Laser-Triggered Drugs Manage Pain in Preclinical Models
Two prospective approaches to pain management use lasers to either release local anesthetics at the site of an injury or block pain signals. Preclinical studies using the techniques, conducted by...
Consumer Sensors Lower Cost of Fluorescence Lifetime Imaging
A fluorescence lifetime system that relies on a consumer-grade time-of-flight sensor and a mathematical model holds promise as a low-cost imaging option for biomedical research and clinical practice....
RapidScan
Envista, Independence LED Partner on Indoor Aquaponics
Independence LED Lighting LLC and Envista Farms LLC have launched an indoor fish and vegetable farming facility that integrates their LED grow lights and aquaponics systems. Aquaponics combines aquaculture (raising fish in controlled environments) with hydroponics (growing plants in water), where the fish effluent helps to feed the plants, which in turn helps clean the water. For the prototype...
EndoChoice Secures 3-Year Tech, Services Contracts
EndoChoice Holdings Inc. has been awarded contracts for its Fuse endoscopy system and services, as well as infection-control products, by the health care improvement company Premier Inc. of...
Heliospectra Wins Grant to Study Greenhouse LEDs, Secures Order
Swedish innovation agency Vinnova has awarded Heliospectra AB a research grant worth 458,000 SEK (about $54,000) to test LEDs for stimulating aroma and nutrients in plants. The goal of the research...
Zeiss Earnings Bolstered by Medical Tech and Microscopy
Increased sales in most segments and favorable currency conversion rates drove profits up about 3 percent at Carl Zeiss AG in fiscal 2015. For the year ended Sept. 30, Zeiss reported earnings before...
UV LED Firm SETi Announces Acquisition, Partnership
Sensor Electronic Technology Inc. (SETI) has signed a long-term agreement with Psoria-Shield Inc. of Tampa, Fla., to develop and manufacture the UV LED light source for the Psoria-Light phototherapy...
Cellvizio Endomicroscope Researched, Commercialized forAdditional Applications
Cook Medical will commercialize a private-label version of Mauna Kea Technologies Inc.'s confocal laser endomicroscopy platform Cellvizio for urological applications. The launch in North America,...
Physik Instrumente Expands to Benelux Region
Motion and positioning systems developer Physik Instrumente (PI) GmbH & Co. KG has created a subsidiary to serve Belgium, the Netherlands and Luxembourg. PI Benelux is led by founders Dick...
Spectroscopy News
Wasp-Inspired Needle Could Advance Spectroscopy for Disease Detection
A robotic surgical system inspired by the anatomy of wood-boring wasps could be used in Raman spectroscopy to detect cancerous and diseased tissue. The wasp-inspired robotic needle is bendable,...
Queensland University Labs Integrate DeNovix Spectrophotometers
Queensland University of Technology (QUT) has adopted 81 DS-11 UV-VIS spectrophotometers from DeNovix Inc. as an undergraduate teaching tool. "As part of a large-scale refurbishment of our teaching...
Application Note: NIR Spectroscopy Aids Diagnosis of Neonatal Brain Injury
A near-infrared (NIR) spectroscopy system has been used to measure cerebral changes and oxygen utilization in vivo, offering a noninvasive diagnostic technique for neonatal brain injury. Researchers...
QCL Features Higher Power, Wider Tuning Range
Combining a tunable laser with an on-chip amplifier has enabled a versatile and powerful tool for spectroscopy and other applications. A team from Northwestern University demonstrated a single-mode...
Postscripts
Narrow Wavelength LED Light is New Rx for Picky Plants
It does not take a brown thumb to know plants are fickle. But this winter many green-thumb gardeners growing fruits or perennials from seed — in a spare bedroom or whatever doubles as their greenhouse — will not realize just how picky their plants are. Even if the seeds sprout, leaves unfurl and buds flower, their fragrance may not reach its full potential. That’s because...
Products
Spectroscopy Lasers
The 08-01 series of ultracompact narrow linewidth lasers from Cobolt AB is designed for high-resolution Raman spectroscopy and other analytical applications. A robust single longitudinal mode (SLM) diode-pumped solid state laser, the DPL 532-nm model is available with an integrated optical isolator for analysis of highly reflective samples. The model offers up to 160 mW after the optical...
Cobolt AB
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Raman Spectrometer
The EAGLE Raman-S spectrometer platform by Ibsen Photonics A/S is available for OEM supply to manufacturers of analytical instruments, including for industrial process control applications. The...
Ibsen Photonics A/S
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Optical Encoder
Celera Motion offers the Veratus optical encoder series from MicroE, designed for ease of installation and robust performance in a range of advanced industrial, medical, microelectronics and...
Celera Motion, Precision Motion
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Light-Sheet Microscope
The Alpha3 LSFM light sheet fluorescence microscope from PhaseView offers high temporal resolution to capture fast dynamic processes in living biological samples. It integrates a fast remote...
PhaseView
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LCOS Projector
The REALiS WUX6010 Pro AV liquid crystal-on-silicon (LCOS) projector from Canon U.S.A. Inc. reproduces images with high detail and color accuracy. Features include a WUXGA resolution of 1920...
Canon U.S.A. Inc., Industrial Products Div.
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Visible Light Spectrophotometer
The LumaSpec LS800S from Prior Scientific Inc. is a compact visible light spectrophotometer, providing quantitative spectral power data for the characterization and monitoring of microscope...
Prior Scientific Instruments Ltd.
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Superresolution Microscope
Bruker Corp. has announced the Vutara 352 quantitative superresolution microscope, allowing pair-correlation, colocation, cluster and live-cell analysis. The device is compatible with the...
Bruker Nano Surfaces
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Confocal Microscope
Caliber Imaging & Diagnostics Inc. has announced the RS-G4 confocal microscope for scientific research. The device has a flexible arm and reduced footprint with fast image acquisition...
Caliber Imaging & Diagnostics Inc.
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Diode Laser Bars
Coherent Inc. offers diode laser bars for medical applications with high batch-to-batch consistency. At 1470 nm with a low fill factor, the 35-W CW-rated bar is designed for fiber coupling,...
Coherent Inc.
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IR LED
The Oslux SFH 4786S IR LED from Osram Opto Semiconductors Inc. enables biometric iris recognition systems to be made simpler and with lower profiles. A height of 1.6 mm allows the device to be...
Osram Opto Semiconductors Inc.
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NIR Imaging System
The Pearl Trilogy from Li-Cor Biosciences expands in vivo imaging capabilities with the addition of a bioluminescent detection channel. The system delivers multitarget imaging options,...
LI-COR Biosciences, Biotechnology
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Fiber Lasers
Amada Miyachi America Inc. has announced the LF series of fiber lasers for precision microwelding. The LF series can be focused to spot sizes as small as 10 μm, and offers precise control of...
AMADA WELD TECH Inc.
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CW Laser Modules
Integrated Optics UAB has introduced the MatchBox2 series of ultracompact CW laser sources for spectroscopy, sorting and illumination. The lasers have a size of 30 × 50 × 18 mm, and...
Integrated Optics UAB
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Cell Culture Microscope
The CKX53 microscope from Olympus Europa SE & Co. KG includes a novel inversion phase contrast imaging technique. Delivering high-quality images over a wide field of view for live-cell and...
Olympus Europa SE & Co. KG
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Handheld PAR Meter
Gigahertz-Optik Inc. has announced the BTS256-PAR handheld spectrometer-based photosynthetically active radiation (PAR) meter for natural or artificial light source analysis. The device...
Gigahertz-Optik Inc.
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MWIR Spectrophotometer
EssentOptics Ltd. has expanded its range of midwave-infrared (MWIR) configurations for the Photon RT spectrophotometer. The IR source was developed and tested to meet customer needs for...
EssentOptics Ltd.
Microscopy Slide
The μ-Slide CorrSight Live slide from Ibidi GmbH allows correlation of the molecular specificity of light microscopy with the high structural resolution of electron microscopy. Live-cell...
ibidi GmbH
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Hard-Tissue Dental Laser
AMD Lasers now offers hard-tissue lasers that are FDA-cleared to perform cavity preparations and bone surgery, as well as other soft-tissue dental procedures. The company offers full-day,...
AMD Lasers
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Microscope Controller
The OptiScan III from Prior Scientific Instruments Ltd. is an entry-level controller for the OptiScan line of motorized microscope stages and focusing devices. Compatible with a range of...
Prior Scientific Instruments Ltd.
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Global Shutter Cameras
Basler AG has expanded its dart and pulse camera series to include e2v Technologies plc's EV76C570 camera sensor with a pixel size of 4.5 × 4.5 μm. The devices can achieve a resolution...
Basler AG
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Tunable Edge Filters
Semrock Inc. has announced the VersaChrome Edge tunable long- and short-pass filters for fluorescence microscopy, hyperspectral imaging, spectroscopy applications and filter prototyping. The...
IDEX Health & Science - Semrock Optical Filters
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