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BioPhotonics: May 2008

BioPhotonics
 May 2008


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FEATURES
Overcoming Optical Challenges to Live-Cell TIRF Microscopy Total internal reflection fluorescence (TIRF) microscopy is a powerful technique. It provides extremely thin axial sectioning with excellent signal-to-noise ratios, allowing observation of...
Can the Miracles Promised by Carbon Nanotubes Be Realized? By delivering drugs directly to the source of disease, carbon nanotubes and other nanoparticles could reduce the toxicity that chemotherapy agents and other drugs introduce to the body. Of all the...
Robust Optics for Microscopy Applications The evolution of microscopy from direct human observation to digital image capture has significantly advanced research in the life sciences. For microscopy, digital cameras, along with...
Trends in Optical Trapping The term “optical trapping” is perhaps misleading: It implies little more than grabbing a molecule or other object and possibly transporting it to some other place. But, as is apparent from studies...
AS WE GO TO PRESS
High-speed camera reveals why lizards use hunting strategies By recording movies of lizards hunting prey on a pint-size race track, researchers from Ohio University in Athens have discovered that the reptiles' physiology influences their predominant hunting style. Lizards use two basic strategies to hunt prey. In the aptly named sit-and-wait approach, they linger until their prey passes by and then sprint toward it and grab it with their tongue. In a...
Headphones could eliminate MRI sounds MRI scanners can make beeping, whirring and grinding sounds as loud as a jet engine. These sounds not only disturb patients but also cause some to squirm, thus ruining the images and wasting time and...
Errata The image accompanying the article "Getting to the root of the solution" on page 24 of the February issue included an incorrect caption. The caption should have read: "Infrared spectroscopy was used...
Forecasting prostate cancer with MRI Cancer treatment outcome is notoriously difficult to predict. The disease spreads rapidly in some and slowly in others. In some cases, the disease is destroyed after treatment, but in others, it...
Fluorescent green gel fashioned from hybrid materials A greenish gel that fluoresces in response to temperature and pH changes has been created by coupling a polymer scaffold with an activated protein. The hybrid material potentially could be used...
BREAKTHROUGHMEDIA
Research products The “08-09 BD Biosciences Clinical & Research Product Catalog” presents the company’s software, consumables, research and clinical instrumentation, and research reagents for flow support, in vivo capture, immunohistochemistry, and cell and molecular biology. Among other products detailed in the 608-page resource are reagents for human stem cell research, antibodies to mouse and rat leukocytes...
Imaging software Intevac Inc. has released a brochure on its VSpec Pro spectroscopy and imaging software. The five-page downloadable document notes that the software is compatible with Microsoft Windows 2000, XP and...
Cell biology products “Bioprobes 55,” the March 2008 issue of a newsletter published by Invitrogen Corp., features articles on new technologies such as Qdot 625 nanocrystals and conjugates, Click-iT EdU assays for...
Drug discovery Issue 20 of “Cell Notes,” a serial publication of Promega Corp., focuses on drug discovery and screening. The 32-page document includes an article on monitoring viability during gene-directed enzyme...
Immunology products The “2008 Immunology Catalog” from Bachem Americas Inc. includes new products for research in areas such as apoptosis, cancer, neuroscience, diabetes and obesity, pituitary and hypothalamic hormones,...
Optics brochure Hellma Optik GmbH Jena has released a 35-page brochure on its corporate capabilities and its optical products. It specifies cylinder optics, including lenses, achromats, arrays and mirrors; toric...
FRET technology The “FRET Technology” brochure from AnaSpec Inc. features the SensoLyte long-wavelength protease assay kits, which combine the company’s Förster resonance energy transfer (FRET) technology and...
Objectives guide A 21-page brochure titled “Objectives from Carl Zeiss: Exceeding Your Expectations” is available from Carl Zeiss MicroImaging GmbH. Downloadable from the company Web site, this guide to selecting...
Laser safety The 181-page volume CLSOs’ Best Practices in Laser Safety is a compilation of laser safety procedures, policies and practical advice created by laser safety experts and certified laser safety...
POST SCRIPTS
Imaging microscopic beauty Beautiful images can be found on any scale, from telescopic photographs of distant stars to microscopic pictures of blood cells. The Wellcome Image awards, known previously as the Biomedical Image awards, is an annual event run by the Wellcome Trust of London. It focuses on the stunning images created by scientists during their research. A clump of prostate cancer cells was imaged by Annie...
PRODUCTS
Terahertz spectrometer TeraView Ltd. has released the TPS Spectra 3000, a terahertz spectrometer that performs nondestructive transmission and attenuated total reflection measurements on solids, liquids, suspensions, slurries, pastes and films. The semiconductor-based, pulsed instrument performs suitable analysis under ambient conditions. The transmission module accepts standard IR sampling accessories, and the...
TeraView Ltd.
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Interferometer The AnaLight 4D dual-polarization interferometer from Farfield Group Ltd. enables scientists to determine molecular conformation, structurally relevant binders, affinity and rate constants,...
Biolin Scientific
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High-resolution scanner The iScan system, a high-resolution scanner that supports rapid, sensitive and accurate imaging of the company’s BeadChip-based genetic analysis products, has been released by Illumina Inc. The...
Illumina Inc.
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Microscopy camera Lumenera Corp. has released the Infinity X-32 pixel-shifting CCD camera. It achieves 32-megapixel resolution by shifting a Sony ICX274 sensor with a 1616 × 1216-pixel array. Users also can operate it...
Teledyne Lumenera
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SD-OCT spectrometer The Super Gamut series spectrometer from BaySpec Inc. is suitable for researchers and OEM users who are assembling spectral-domain OCT, white-light interferometry or NIR spectroscopy systems. With no...
BaySpec Inc.
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Spectrometers The uncooled Maya2000 and Maya2000Pro miniature spectrometers from Ocean Optics Inc. are suitable for low-light-level applications such as fluorescence, DNA sequencing and Raman analysis. The...
Ocean Insight
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Micromirror device Texas Instruments Inc. has released the Discovery 4000, a development platform that includes the company’s digital micromirror device (DMD). When integrated with light sources and optics, the DMD...
Texas Instruments Inc., DLP Products
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FLIM systems Fluorescence lifetime imaging microscopy (FLIM) systems for the Zeiss LSM 710 laser scanning microscopes have been introduced by Becker & Hickl GmbH. Based on the company’s multidimensional...
Becker & Hickl GmbH
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Linear translation stages Linear translation stages with travel track lengths of 6, 12 and 24 in. are available from Edmund Optics Inc. The Techspec series stages use rack-and-pinion positioning with accuracy of 0.01 in. and...
Edmund Optics Inc.
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Temperature controllers Available from Power Technology Inc., the TC series temperature controllers feature a proportional integral control loop for use with thermoelectric coolers. Delivering 3.5 A at 7 V, they provide...
Power Technology Inc.
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Microfluidics ALine Inc. has released a family of microfluidic cuvettes for fluorescence and absorbance applications. The FluoroVette, which has a 50-μl sample chamber, is UV/VIS transparent from 220 to 1000...
Multi IR Technology Co. Ltd.
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Yellow laser Coherent Inc. has introduced Compass 561-50, a frequency-doubled diode-pumped solid-state yellow laser. The 100 × 40 × 32.5-mm device delivers 50 mW at 561 nm, with a noise specification of 0.25% rms...
Coherent Inc.
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Low-power lasers Spectra-Physics has expanded the Excelsior product family with the introduction of the Excelsior-505 platform for DNA sequencing. The 505-nm diode-pumped solid-state laser is available with output...
MKS/Newport
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Spectrophotometer Shimadzu Scientific Instruments Inc. has released the IRAffinity-1 Fourier transform infrared spectrophotometer. It offers resolution of 0.5 cm–1 and a signal-to-noise ratio of 30,000:1, resulting...
Shimadzu Scientific Instruments Inc.
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X-ray camera The Shad-o-Box 1024 x-ray camera from Rad-icon Imaging Corp. offers stand-alone high-resolution imaging and a parallel digital interface. The 49.2 × 49.2-mm sensing area consists of a 1024 ×...
Teledyne Rad-icon Imaging
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Microscope stage Prior Scientific Inc. has introduced the H117LSM ProScan II, a flattop motorized stage designed for Carl Zeiss laser scanning microscopes. Its design enables the use of micromanipulators,...
Prior Scientific Inc.
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Micromanipulator stage Available from Steinmeyer Inc., the MT 130-50-DC micromanipulator stage offers travel of 50 mm with positioning accuracy of 10 μm, and repeatability and straightness/flatness runout of ±1...
Steinmeyer Inc.
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Scanning microscope The LSM 710 from Carl Zeiss MicroImaging GmbH is a laser scanning microscope designed for fluorescent biological samples. The device features a spectral detector with two, three or 34 channels and...
Carl Zeiss Spectroscopy GmbH
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Optical filters Semrock Inc. has released a line of optical edge filters for Raman spectroscopy and fluorescence imaging. The EdgeBasic long-wave pass filters have a typical transmission of 98% and an optical...
IDEX Health & Science - Semrock Optical Filters
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Confocal microscope The TCS SP5 X, a confocal microscope with a supercontinuum laser that allows for greater flexibility with fluorescence microscopy, is available from Leica Microsystems GmbH. The device allows any...
Leica Microsystems GmbH
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Diode laser A single bar-based fiber-coupled diode laser module from Dilas delivers up to 50 W of CW power at 808 and 976 nm through a 400-μm SMA fiber with a numerical aperture of <0.22. Intended for...
DILAS Diode Laser Inc.
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OEM diode series Toptica Photonics AG has extended its iWave narrow-linewidth OEM series with a 375-nm version. Suitable for use in Raman microscopy, Raman spectroscopy or in instruments with linewidth-sensitive...
Toptica Photonics AG
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FTIR software ABB Inc. has unveiled the Horizon MB FTIR (Fourier transform infrared) software for the MB3000 series FTIR spectrometers. The extended software features flexible library search capabilities, work...
ABB inc., Measurement & Analytics
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Imaging system UVP LLC has announced the latest addition to its BioSpectrum imaging series with the BioSpectrum 800. The system is a fully motorized and automated light-tight darkroom with a high-resolution...
Analytik Jena US LLC
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Spectrum-stabilized laser The BRM Cleanlaze USB Raman excitation laser series from B&W Tek Inc. is based on spectrum stabilization technologies. Available in OEM and in end-user packages with wavelengths of 785, 808, 830...
B&W Tek LLC
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Dermatology server Lucid Inc. has launched the VivaNet secure telemedicine server and network for the management and transfer of clinical data from dermatology practitioners using the company’s confocal imagers to...
Caliber Imaging & Diagnostics Inc.
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Nanopositioning stages PI (Physik Instrumente) LP has expanded its PIHera family of compact X, X-Y, Z and X-Y-Z flexure-guided piezo nanopositioning tables with the addition of models with travel ranges up to 1800 μm....
PI (Physik Instrumente) LP, Motion Control, Air Bearings, Piezo Mechanics
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Light source Exalos AG has expanded its line of superluminescent light-emitting diodes with the release of the EBS8505, an ultrabroadband light source for use in medical imaging and instrumentation applications....
Exalos AG
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Doubled optical tables The ST-UT2 doubled optical tables from Newport Corp. incorporate tuned mass dampers to reduce vibrations as well as honeycomb cells for a lighter, stiffer table with improved dynamic rigidity....
MKS/Newport
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Photocoagulator OptiMedica Corp. has announced the Pascal system, which is used with National Instruments’ LabView FPGA and PCI-7833R data-acquisition device to improve panretinal laser photocoagulation treatment....
Abbott Medical Optics (AMO)
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Molecular imaging Bruker Daltonics has unveiled a Maldi imaging solution for its apex-ultra Fourier transform mass spectrometer. The device is equipped with a SmartBeam Maldi ion funnel source suitable for tissue...
Bruker Daltonics Inc.
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Spectrofluorometer The FluoroMax-4 spectrofluorometer from Horiba Jobin Yvon Inc. has a minimum signal-to-noise ratio of 3000:1 and a sensitivity of at least 400,000 cps for the water-Raman peak at 397 nm. With...
HORIBA Scientific
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Green laser Del Mar Photonics Inc. has introduced a 532-nm continuous-wave diode-pumped solid-state laser with a 4-/6-W optical pump source. The fiber-fed laser generates a near-diffraction-limited beam with a...
Del Mar Photonics Inc.
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Benchtop SEM JEOL and Nikon Instruments Inc. have collaborated to introduce the NeoScope, a benchtop scanning electron microscope that can be used for bioscience applications. The device offers magnification of...
JEOL USA Inc.
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Digital microscope The VHX-600 series digital microscopes from Keyence Corp. of America offer a depth of field that the company says is at least 20 times greater than that of conventional microscopes. The 54-megapixel...
Keyence Corp.
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BIOPHOTONICS 2008
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