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BioPhotonics - Nov/Dec 2017
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3D Imaging Aids Life Sciences
While human bodies and single cells are three-dimensional, imaging of them often was not. Data might be captured in two-dimensional slices during a computed tomography, magnetic resonance, ultrasound...
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DGC Helps Illuminate Mechanisms of Alcohol Dependency
Imaging transparent, colorless specimens has always presented a challenge in optical microscopy. In many applications, it is not desirable or even possible to use fluorescent dyes, stains or...
Full-Spectrum Technology Deepens the Reach of Flow Cytometry
Flow cytometry is gaining traction as a clinical and research tool in areas such as immuno-oncology and systems biology because it enables the ability to profile a large panel of heterogeneous cells...
Photomediated Ultrasound Therapy Offers Precision Targeting of Microvessels
Neovascularization and vascularization play a critical role in the pathogenesis of numerous pathological conditions, including cancer, inflammation and retinal vascular diseases. Retinal diseases...
Editorial
The Virtues of Synergy
Our cover story this month focuses on a hybrid technique: photomediated ultrasound therapy (PUT). As the name implies, the technique takes advantage of the syngeries of lasers and sound to increase the effectiveness of antivascular therapy. Developed by a research team at the University of Michigan and other institutions, PUT may provide new treatments for cancer and diseases causing blindness...
BioScan
Photoacoustic Imaging Technique Measures Periodontal Health
Using squid ink as a contrast agent for a photoacoustic ultrasound, researchers have developed a dental imaging method for assessing gum health that is non-invasive, comprehensive and accurate. The photoacoustic method can image the entire pocket depth around the teeth at once, without the poking and prodding that typically accompanies the use of a periodontal probe, considered the “gold...
Smartphone App Objectively Assesses Brain Injuries in The Field
A smartphone app that detects concussion and other traumatic brain injuries could be used to determine whether someone — whether a football player, a soldier in battle, or an elderly person who...
Optogenetics Used to Control Interorganellar Communication
Researchers are using optogenetics to tune communication between organelles within living cells. The optogenetics tools are being used to control the proteins that form the bridge between organelles,...
Bioimaging Technique Tracks Multiple In Vivo Interactions
A new approach to optical imaging makes it possible to quickly and economically monitor multiple molecular interactions in a large area of living tissue. This technology could have applications in...
3D Printer Yields Ultracompact Microfluidic Device
A custom 3D printer built using digital light processor stereolithography (DLP-SLA) has demonstrated the ability to print a viable microfluidic device small enough achieve flow channel cross sections...
Fluorescent Sensor Detects Drug-Induced Protein Stress in Cells
A fluorescent sensor that becomes activated in a cell when misfolded proteins begin to aggregate could be an effective way to detect protein aggregates caused by drug-induced proteome stress prior to...
Light-Activated Gene Expression Could Uncover Cancer Therapies
In a novel approach to light-inducible gene regulation, researchers began by modifying the surface of nanorods to make them more efficient in transporting cancer-killing genes to cells. The gold...
RapidScan
NIH Awards $15M in Human Disease Modeling Grants
The National Institutes of Health (NIH) have announced 13 two-year awards totaling about $15 million per year to develop 3-D microphysiological system platforms that model human disease. These...
Purdue to Create Risk-On-A-Chip Device
Researchers at Purdue University are using nanosensors in a device that they hope will help identify risk factors that cause breast cancer. The device, known as risk-on-a-chip, is a small plastic...
Columbia Scientists Use Andor Camera to Develop 3D Microscope
A team of scientists at Columbia University have successfully developed the Swept Confocally Aligned Planar Excitation (SCAPE) 3D microscope, which eliminates the need to mount samples or other...
FlyPulse Partners With FlytBase on Defibrillator Transport Drones
FlyPulse, an emergency drone developer, has partnered with FlytBase, a provider of drone software development platforms, to power its network of defibrillator transport drones. LifeDrone AED is a...
Panorama to Acquire Hydrix
Microelectromechanical systems (MEMS) sensor developer Panorama Synergy Ltd. has entered into a binding agreement to acquire the business of Hydrix Group Pty Ltd. and its related corporate bodies....
European Research Consortium Pursues Chip-Sized Microscope
ChipScope, a European research project under the leadership of the University of Barcelona, aims to develop a completely new and extremely small optical microscope capable of observing the interior...
BioOpinion
Design a Patent and Publication Strategy
It’s difficult to fund and grow your company without a strategic plan for product development, clinical studies, manufacturing, regulatory filings, marketing and sales. Just as important is a strategy for developing patents and publications. For a commercial company, patents and publications go hand in glove to protect your intellectual property, establish market exclusivity and boost...
Postscripts
Laser Imaging ‘Bowl’ Tests For Breast Cancer
Lasers, photonics and ultrasounds are not the typical instruments used during a mammogram. But they could aid doctors in diagnosing breast cancer painlessly, almost effortlessly, and while the patient waits. European researchers from seven different countries are working to develop an imaging device made up of a comfortable hemispherical bowl lined with laser sources and ultrasound detectors. It...
Imaging Sourcebook
Imaging Trends Broadening R&D Applications
Imaging is an expansive market where technological advances in microscopy, lasers and other techniques are resulting in a growing number of applications and functions. Among imaging techniques, multiphoton excitation microscopy is becoming increasingly popular for biomedical research in areas such as neuroscience, where deeper and quicker imaging is needed. Fluorescence microscopy is a developing...
Products
Gel and Blot Imaging System
The G:BOX Mini from Syngene is a compact, upgradeable, multi-application system for all types of gel and Western blot imaging. Featuring a motorized stage, high-performance camera and the...
Syngene USA
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Laser Diode Module
The IQ1C250(473-300) laser from Power Technology Inc. is an instrument quality laser diode module for high-end OEM applications. The IQ1C250(473-300) features a collimated beam with diffraction...
Power Technology Inc.
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Wavelength Combiner
The L6Cc Wavelength Combiner from Oxxius SA combines up to six laser sources in a compact package. The all-in-one combiner integrates LaserBoxx modules from Oxxius as well as lasers from other...
Oxxius SA
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Microscope Cameras
The Axiocam 702 mono and Axiocam 512 color microscope cameras from Carl Zeiss AG complement the current portfolio of high-speed USB 3.0 microscope cameras. The Axiocam 702 mono features...
Carl Zeiss AG, Camera Lenses
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Low-Profile Manipulator
The MX130 series of low-profile micromanipulator from Siskiyou Corp. facilitates the positioning of multiple probes in the space-constrained and often crowded space around a microscope sample. ...
Siskiyou Corp.
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Insight sCMOS Camera
The Insight sCMOS camera from Spot Imaging features the Sony Pregius sensor for digital imaging technology. The camera’s USB 3.0 interface and global shutter work with the SPOT software...
SPOT Imaging
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Mini XY Stage
The U-723 mini XY stage from Physik Instrumente LP is an ultra-compact XY scanner and positioner powered by small integrated direct-drive ultrasonic piezoceramic motors. The patented drives...
PI (Physik Instrumente) LP, Motion Control, Air Bearings, Piezo Mechanics
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Spectroscopy Software
PicoQuant GmbH has added remote interface to the system software for the FluoTime 300 spectrometer, allowing connection to external accessories. The FluoTime 300 is a high-end, time-resolved...
PicoQuant GmbH
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Camera Lenses
Framos GmbH has announced the MPY lens series from Computar with 12-MP resolution, designed to work with the Sony Pregius IMX253 and IMX255 image sensors. The 1.1-in. C-mount series enables the...
FRAMOS GmbH
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Pharmacode Vision Sensor
The EyeSens PharmaCode Reader (PCR) from EVT Eye Vision Technology GmbH is a vision sensor that reads pharmarcode, the seven-digit numerical code for unambiguous identification of pharmaceutical...
EVT Eye Vision Technology GmbH
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