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BioPhotonics - Nov/Dec 2021
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Digital Edition
Features
Laser Therapy Reaches Hard-to-Treat Epilepsy
For decades, the most commonly used treatments for epilepsy were pharmaceuticals or resection surgery, which involves removing a segment of brain tissue from where the patient’s seizures originate....
Neurophotonic Techniques Shed New Light on Traumatic Brain Injury
Traumatic brain injury can have catastrophic impacts on everyday functioning and quality of life. Now, a set of photonic tools may provide fresh insights into this condition. Along with the technical...
Biomedical Research, Innovation to Take Center Stage at SPIE BiOS
A rapid-fire Hot Topics session featuring talks on the latest in biomedical optics, from live analysis of embryonic development to deep learning-enabled optics, will be a centerpiece at SPIE BiOS...
Two-Photon Imaging Monitors Brain Synapses During Prolonged Anesthesia
The formation of synapses in the circuitry of the brain, and especially the solidification and disappearance of synaptic structures, mediates how people learn, memorize, and forget. Since the...
Fluorescence Lifetime Imaging Reveals the Cutting Edge in Cancer Surgery
Fluorescence lifetime imaging (FLIm) is an optical spectroscopic technique that is well suited to interrogating biological tissues in vivo. By measuring the time-resolved fluorescence properties...
NIR Spectroscopy Captures the Impacts of Stroke
Every year, approximately 5.5 million people worldwide lose their lives to stroke. According to the Centers for Disease Control and Prevention, stroke-related costs in the U.S. total nearly $50...
Editorial
Lasers on the brain
Existing treatments, such as laser ablation, and therapies currently in research and development both hold promise for patients and clinicians who seek to successfully cross the divide between living with epileptic seizures and experiencing an improved quality of life. Laser-based techniques also present a viable alternative to traditional, often risky, resection surgery, in which a portion of...
BioScan
Microscopy Method Enables Deep In Vivo Brain Imaging
A method developed by the Prevedel Group at the European Molecular Biology Laboratory (EMBL) allows neuroscientists to observe live neurons deep within the brain — or any other cell hidden within an opaque tissue. The method is based on three-photon microscopy and adaptive optics. The method increases the ability of scientists to observe astrocytes generating calcium waved in deep layers of...
Dyeless Method Maps Blood Flow in Brain Down to Single Cell
Researchers from the Skolkovo Institute of Science and Technology (Skoltech) and Saratov State University developed an inexpensive method of visualizing blood flow in the brain, one that avoids the...
OSA Changes Name to Optica
The professional society in optics and photonics formerly known as The Optical Society (OSA) has changed its name to Optica, the Society advancing optics and photonics worldwide. The global...
Injectable Biosensors Convert Brain Activities into Detectable Optical Signals
Technology for monitoring neuronal activity noninvasively could allow scientists to study the brain without the need for surgery or implanted devices. The newly developed nanotechnology, called...
Optical Technique Measures Chirality Over Broad Wavelength Range
A research team from Politecnico di Milano and the University of Bayreuth (Germany) has developed an approach for the quick measurement of chirality across a broad wavelength range. In molecules,...
3 Combined Techniques Boost Imaging Precision
Researchers from the University of Illinois Urbana-Champaign, working with domestic and international collaborators, have combined three imaging techniques to detect the timing and location of brain...
Photoacoustic Technology Images Brain with Laser Light
Caltech professor Lihong Wang has demonstrated a technology capable of imaging the human brain with laser light and ultrasonic sound waves. The technology is known as PACT, for photoacoustic...
3 Questions
3 Questions with Euiheon Chung
BioPhotonics spoke with Euiheon Chung, a biomedical science and engineering professor at Gwangju Institute of Science and Technology in South Korea. Chung and his colleagues recently published a paper (www.doi.org/10.1364/ optica.422871) about the use of a technique called optical speckle image velocimetry to quantitatively measure blood flow in the cortical brain as an indicator of health or...
BioOpinion
Photostimulation provides an alternative to medication
Clinicians have long sought to understand the physiological causes of brain dysfunction. The adverse effects are sometimes attributed to traumatic brain injury or to aging. While some of the dysfunctional processes are becoming better understood, much is still to be learned about treatment and prevention of lasting effects on the brain from accidents or illnesses. It is time for doctors and...
Postscripts
Researchers go eye to eye with octopuses
The loss of macular pigment is a precursor to macular degeneration, a disorder that afflicts millions every year. Historically, there has been no easy way to test for loss of pigment as part of a traditional eye examination. Researchers at the University of Bristol in England found a way to help identify risk in humans by studying octopuses captured during low tide on coral reefs around Lizard...
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The NanoDrop Eight UV-Vis Microvolume Spectrophotometer from Thermo Fisher Scientific Inc. allows molecular biologists to measure the concentrations and purity of their biological samples, identify and correct for contaminants, and differentiate between DNA and RNA. The device simultaneously evaluates eight samples in 20 s or less, enabling academic and industrial researchers to analyze...
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Intraoral 3D Scanner
The Aoralscan 3 intraoral 3D scanner from SHINING 3D Tech. GmbH allows clinical users to easily and quickly acquire digital impressions. Intelligent data processing capabilities are designed...
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Ultrastable Laser
The ORS-Mini ultrastable laser from Menlo Systems GmbH features a <2 Hz linewidth. Designed as a compact 19-in. rack module for field applications, the system features a 5-cm high-finesse...
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Performance Chiller
The Nextreme NRC400 Performance Chiller from Laird Thermal Systems Inc. is an environmentally friendly recirculating chiller delivering precise temperature control for leading analytical and...
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Fluorescent IR Dyes
The CF® 850 and CF® 870 fluorescent IR dyes from Biotium Inc. are novel long wavelength dyes with >850 nm emission maxima for life science researchers. With high brightness, aqueous...
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Medical Rectifier
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Non-Adhesive Microscopy Surface
The non-adhesive Bioinert surface from ibidi GmbH is now available for its µ-Slides, providing a thin polyol hydrogel layer for microscopy that does not allow binding of cells or biomolecules....
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Microscopy Staining Kits
ExoBrite™ EV Membrane Staining Kits from Biotium Inc. are designed for fluorescent staining of exosomes or extracellular vesicles with little to no background. The kits provide an...
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Live-Cell Imager
The CytoSMART Lux3 BR live-cell imager from CytoSMART Technologies BV is a small brightfield microscope equipped with a high-quality, 6.4-MP CMOS camera that allows researchers to perform long-term...
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Terahertz Spectrometer
The C16356 Handy Probe Terahertz Spectrometer from Hamamatsu Photonics KK features a separate, handheld probe head connected to the main unit by an optical fiber. Compared to conventional...
Hamamatsu Corporation
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Cryogenic Raman Imaging System
The cryogenic Raman imaging system cryoRaman, jointly introduced by attocube systems AG and WITec GmbH, integrates attocube's cryostat and nanopositioner technology with the vaunted sensitivity and...
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