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BioPhotonics: October 2010

BioPhotonics
 October 2010


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FEATURES
Optogenetics: A Conversation with Ed Boyden In a few short years, optogenetics has gone from a glimmer in the eye in a handful of researchers to a viable technique used worldwide to study information processing in the brain. We recently caught...
Next-Generation IR Microscopy: The Devil Is in the Detail One of the most important attributes of infrared spectroscopy is its ability to handle physically small samples or small features on samples. Important applications include forensic analysis of a...
Combining Second-Harmonic Generation with Multiphoton Imaging Second-harmonic generation (SHG) is a method of imaging structures in tissue using a pulsed near-infrared laser. The technique can be combined with various methods of fluorescence imaging to deduce...
Body Vision: IR Applications and Lens Selection in Biomedical Settings Although IR optics have long been used for military, surveillance and industrial applications, it is only recently that their full potential is being explored in biomedical settings. Common...
Characterization of Intraocular Lenses: Different Measurement Methods Intraocular lenses (IOLs) are artificial implants used to replace the human eye crystalline lenses in patients with cataracts. The standard IOL is designed to match the patient’s eye to provide...
Telehealth: Seeing, and Treating, Patients at a Distance Rhonda Johnston, a nurse practitioner, has a simple requirement when it comes to the technology that allows her to serve patients scattered across southern Colorado: “Our goal is to make sure...
EDITORIAL
New ripples rock optogenetics, IR microscopy The circle of life in scientific research could perhaps be illustrated by the spreading ripple created by dropping a stone in a lake, the next ring wider than the one before. The rock – the discovery – lives on in its technological progeny, enabling researchers to widen their investigations, dropping new rocks, making new waves. Such is certainly the case with the nascent science of...
BIOSCAN
Multicolor quantum dots ID rare cancer cells Multicolor quantum dots linked to antibodies can distinguish the Reed-Sternberg cells characteristic of Hodgkin’s lymphoma, according to researchers at Emory University and Georgia Institute of...
Imaging programmed cell death – live Studying apoptosis, or programmed cell death, is imperative for understanding normal physiological functions as well as disorders such as cancer and neurodegenerative and autoimmune diseases. Being...
The new frontier for imaging resolution: 0.5 nm Efforts to develop microscopes that offer “superresolution” capability have a new paragon: Investigators at Stanford University, led by US Secretary of Energy Steven Chu, have devised a...
Nanotubes put cancer under the spotlight Blasting tumors with light from a laser is an experimental technique that has taken an important step forward, thanks to a team from Wake Forest University Baptist Medical Center. The researchers...
Tel Aviv scientists put matter in its place The ability to manipulate matter using lasers is enabling scientists at Tel Aviv University to develop innovative photonic devices. Dr. Yael Roichman and colleagues at the university’s school...
Hydrogen replacement improves fluorescent dyes’ detection, stability and shelf life Investigators have increased the shelf life and detection ability of fluorescent probes that are necessary for studying a variety of inflammatory diseases, including cancer and atherosclerosis, by...
RAPIDSCAN
Stimulus money funds 3-D microscope A new microscope at Indiana University will allow researchers to examine biological samples in 3-D with unprecedented detail, and it would not be there without stimulus funding. Funding of $1.2...
Olympus NDT In Massachusetts, Waltham-based Olympus NDT announced that it has purchased Innov-X Systems Inc. of Woburn, a portable x-ray fluorescence analytical instruments manufacturer. The latter company will...
University of Southampton Following an increased interest in its SpectroSens optical microchip platform technology, Stratophase, a venture capital-funded spinout from the University of Southampton in the UK, has doubled its...
Asylum Research Corp. Santa Barbara, Calif.-based Asylum Research Corp., a scanning probe/atomic force microscopy (AFM) provider, has delivered a Cypher AFM and an MFP-3D-BIO AFM to the Department of Chemical and...
FEI Co. FEI Co. of Hillsboro, Ore., a scientific instrumentation supplier, has released four software applications that increase the throughput and ease of use of its electron microscopes for biological...
Omega Optical Inc. Omega Optical Inc. of Brattleboro, Vt., has received a $750,000 Phase II Small Business Innovation Research award from the National Cancer Institute for the development of a high-speed fiber...
Agilent Automation Solutions Agilent Automation Solutions of Royston, UK, has posted a recorded webinar to its website that enables scientists to learn techniques for introducing reliable automation into small- and large-scale...
Genetix Imaging and image analysis solutions provider Genetix of New Milton, UK, has received US patent No. 7,776,584, aspects of which have been incorporated into the company’s ClonePix FL, a system...
Olympus America’s Scientific Equipment Group Olympus America’s Scientific Equipment Group received two awards at the first European Scanner Contest, which took place in Berlin in conjunction with the 94th annual meeting of the German...
AnaSpec Inc. Fremont, Calif.-based AnaSpec Inc., provider of the long-wavelength, ultrasensitive SensoLyte assay kit, announced that it will now offer custom assay development. The company’s Senso-Lyte...
POST SCRIPTS
Your Prion Eyes When you gaze into someone’s eyes, you can tell much about their character. It just so happens that you also might be able to tell whether they have a neurological disease. Jacob W. Petrich and his colleagues at Iowa State University in Ames have shown that basic noninvasive fluorescence spectroscopy can show whether animals have been infected with a form of transmissible spongiform...
PRODUCTS
UV-VIS Spectroscopy Thermo Fisher Scientific Inc. has launched its Evolution 200 series next-generation ultraviolet/visible spectro-photometers featuring new Insight software with Customized User Environment scripting...
Thermo Fisher Scientific
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Photomultiplier Tubes Hamamatsu Photonics K.K.’s Electron Tube Div. has introduced a photomultiplier tube with enhanced UV sensitivity. The R11540 is a 28-mm-diameter side-on device with a spectral response ranging...
Hamamatsu Corporation
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Microplate Reader BioTek Instruments Inc. has released the Synergy H1 hybrid multimode microplate reader, a monochromator-based instrument for ultraviolet/visible absorbance, top and bottom fluorescence, and...
BioTek Instruments Inc.
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Aspheric Lenses LightPath Technologies Inc. has unveiled a family of four aspheric lenses designed for blue laser diodes operating at 405 or 488 nm. The compact lenses are designed as the primary optics for...
LightPath Technologies Inc.
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AFM System Veeco Instruments Inc. has unveiled the Dimension Edge atomic force microscope (AFM) system for physical and life sciences applications. It features hardware and software advances that reduce the...
Veeco Instruments Inc.
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Microscope Series WITec GmbH has introduced an extension of its alpha300 microscope series. Building on the system’s inherent modularity, the company has added several new microscope versions to meet diverse...
WITec GmbH
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Travel Stages Applied Scientific Instrumentation offers an assortment of stages with flat tops and extended range of travel for robotic loading. The MS-2500 provides 100 mm of Y-axis travel and 250 mm of X-axis...
Applied Scientific Instrumentation Inc.
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Laser Diodes The LaserBoxx series, announced by Oxxius SA, are laser diode modules offering high optical performance in a driver integrated compact box. With a size of only 40 x 40 x 100 mm, they allow easy...
Oxxius SA
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Alignment System The F-206.S, a six-axis hexapod alignment system from PI (Physik Instrumente) L.P., is a precision positioning system that provides 6-D motion with 33-nm resolution and an extensive alignment...
PI (Physik Instrumente) LP, Motion Control, Air Bearings, Piezo Mechanics
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Life Sciences Interface Carl Zeiss AG has introduced an integrated hardware/software interface to connect light and scanning electron microscopes for materials analysis and correlative microscopy in the life sciences....
Carl Zeiss AG, Camera Lenses
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Imaging Workstation Till Photonics Inc.’s iMIC-Andromeda imaging workstation combines a broad range of imaging applications. The modular approach enables integration of methods such as total internal reflection...
FEI Munich GmbH
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NIR Imaging The BioSpectrum imaging system from UVP is configured for use in multiple imaging applications. Combined with the BioLite multispectral light source, it provides a powerful system to excite and...
Analytik Jena US LLC
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64-Channel Converter Voxtel Inc.’s plug-and-play YVX-657 time-to-digital converter has 64 channels and provides <35-ps time resolution per channel. Available immediately for delivery to OEM systems integrators,...
Voxtel Inc.
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Positioning Stages Airex Corp.’s P3 Series plug-and-play linear motor positioning stages offer design features to handle the high-duty-cycle operations required in competitive precision manufacturing...
Airex Corp.
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Ultrafast Amplifier A new Ti:sapphire ultrafast laser amplifier from Coherent Inc., the Legend Elite Duo-HP, offers >15 W of output power and pulse energy of up to 10 mJ. The kilohertz-class thermoelectrically cooled...
Coherent Inc.
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Laser Diodes Laser Components (UK) Ltd.’s range of fiber-coupled high-power laser diodes has been enhanced with the addition of the K41 and CS405 series. At 405 nm, output power from the fiber varies from...
Laser Components (UK) Ltd.
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VUV Spectrometer McPherson Inc. has announced that its vacuum-ultraviolet (VUV) spectrometer, Model 234/302, is now available with improved efficiency over a wide wavelength range. New platinum-coated gratings are...
McPHERSON
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X-ray Microscope A new computed tomography system that delivers synchrotron like 3-D imaging at 50-nm resolution within a laboratory setting has been introduced by Xradia Inc. The UltraXRM-L200 uses state-of-the-art...
Carl Zeiss X-ray Microscopy LLC
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Deconvolution Module Olympus Europa Holding GmbH’s cellSens deconvolution module employs a constrained iterative algorithm to remove out-of-focus blur in advanced life sciences imaging. This high-speed operation...
Olympus Europa SE & Co. KG
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Picosecond Laser RPMC Lasers Inc. now offers affordable, rugged, compact, air-cooled, high-energy picosecond lasers providing up to 150 μJ of pulse energy. These short-pulsed lasers combine the advantages of fiber...
RPMC Lasers Inc.
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BIOPHOTONICS 2010
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