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DIGITAL EDITION
FEATURES
Fluorescence Microscopy: Getting the Picture Right
Fluorescence microscopy is a very broadly used term covering numerous applications. It ranges from basic life science applications such as time-lapse cell viability assays — in which dead cells are...
Q&A Spectroscopy gives clear view of data
Spectroscopy is a broad field comprising a variety of methods and modalities, and covering applications from industry process control and security to biomedical. Each modality has its particular...
Neuroscience 2019 Celebrates SfN’s 50th Anniversary
This fall, scientists and researchers from around the world will gather at the Neuroscience 2019 conference to hear lectures such as “Wavefront Engineering: Illuminating the Neural...
VIS-OCT Opens Eyes to New Approaches
First reported in 1991 by Huang and colleagues, OCT has become an important imaging tool for ophthalmology following innovations over the past three decades. OCT noninvasively provides 3D in vivo...
Lens-Free Microscopy Focuses on Commercialization
With advancements in image processing and sensors, lens-free microscopy is ready for a closer look by researchers, industry, and consumers. Compared to traditional benchtop microscopes, lens-free...
Open-Source Photon Counting Advances Biological Research
A surgeon removing a malignant tumor, a security agent detecting harmful molecules at a stadium, an autonomous car avoiding a collision, a weather satellite spotting hurricane formations, a...
EDITORIAL
VIS-OCT offers sight line
The benefits of optical coherence tomography (OCT) have long been known as an imaging tool in ophthalmology, enabling the examination of the eye at microscopic resolution. But what may not be widely appreciated is that the use of visible light sources can improve upon the results of this well-developed technique in the detection and understanding of various eye-related diseases such as macular...
BIOSCAN
Two-Photon Microscope Captures Brain Activity at Record Speed
A new two-photon microscope from scientists at Howard Hughes Medical Institute’s Janelia Research Campus records footage of brain activity 15 times faster than once believed possible, the team...
Terahertz Imaging System on a Chip Offers Speed and Portability
An imaging system developed at Princeton University uses lasers small enough to fit on a microchip, and emits and detects electromagnetic radiation at terahertz (THz) frequencies. The new system,...
Light-Activated Dynamic Looping Triggers Gene Expression
Using a technique called light-activated dynamic looping, or LADL, scientists at the University of Pennsylvania are investigating the role that genome folding plays in gene expression. The team has...
Superresolution Imaging Method Aids in Water Decontamination
An imaging technique developed by Cornell University researchers shows promise as a tool for decontaminating water. The new approach allows imaging of catalytic reactions at the nanoscale in real...
Antibody-based Probe Developed for Live-Cell Imaging in Vivo
To expand the toolbox of imaging in living cells, researchers from Colorado State University and the Tokyo Institute of Technology have developed a genetically encoded, antibody-based probe that...
Optochemogenetics Tested for Neuronal Repair after Stroke
Researchers at Emory University School of Medicine have developed optochemogenetics, a combinatorial approach based on optogenetics and chemogenetics, which enables the selective, noninvasive...
IR Imaging Technology Could Improve Breast Cancer Detection
Researchers at Rochester Institute of Technology (RIT) and physicians from the Rochester Regional Health System (RRHS) have developed a noninvasive, cost-effective method using infrared (IR)...
Wearable NIRS Device Reveals How Seals Prepare to Dive
Scientists at the University of St. Andrews have created a wearable, noninvasive device based on near-infrared spectroscopy (NIRS) that can be used to investigate blood volume and oxygenation...
RAPIDSCAN
Olympus Invites Entries for Global Light Microscopy Image of the Year
Olympus has launched its first Global Image of the Year Life Science Light Microscopy Award, expanding upon the Image of the Year European Life Science Light Microscopy Award, which began in 2017....
Agilent Technologies to Acquire BioTek Instruments
Agilent Technologies Inc., a research, development, and manufacturing company, has agreed to pay $1.2 billion to acquire BioTek Instruments Inc., a maker of cell imaging systems.
Prellis Biologics Receives $8.7M, Reports Tissue Printing Progress
Prellis Biologics, developer of a holographic organ printing system, has received an $8.7 million investment led by Khosla Ventures. The investment is a Series A, and comes after Prellis announced...
SCANLAB Appoints Sonner R&D Director
SCANLAB GmbH, an OEM manufacturer of laser scan systems, has appointed Christian Sonner head of research and development to strengthen the company’s market position in digital products and...
Doctoral Student Wins Nano Innovation Award for Highly Sensitive Microscope
Thomas Hümmer, a doctoral student at the Ludwig-Maximilians-Universitat (LMU) Munich and Max Planck Institute of Quantum Optics, has been awarded €6000 for developing a highly sensitive...
Precision Optics Acquires Portion of Ross Optical for $2M
Precision Optics Corp. Inc., a designer and manufacturer of advanced optical instruments for the medical and defense industries, has completed the acquisition of certain assets of Ross Optical...
Spectral Evolution Moves to Expanded Facilities
Spectral Evolution has moved operations to expanded facilities in Haverhill, Mass., to provide more space for engineering, test, and manufacturing. Established in 2004, Spectral Evolution is a...
TOPTICA Photonics Opens Facilities in China
Laser developer and producer TOPTICA has expanded into China with a head office in Shanghai and a branch in Beijing to provide sales, service, and application support for its full range of...
Juergen Czarske Receives OSA Award
The Optical Society (OSA) has named Juergen Czarske of Technische Universitat Dresden (TU Dresden) the recipient of the 2019 Joseph Fraunhofer Award/Robert M. Burley Prize for seminal contributions...
Innovations in Optics Hires Donahue as Manufacturing Operations Director
Innovations in Optics Inc. has hired Dennis Donahue as director of manufacturing operations. He will report directly to CEO Thomas Brukilacchio.
BIOPINION
Illumination in microscopy often overlooked
As scientists engage in the development and manufacture of high-performance lighting, we find it frustrating to encounter a lack of appreciation for the illumination source in the successful application of light microscopy. Like that other pervasive illumination source, the sun, microscope light sources are commonly taken for granted. It often seems they only draw attention when they are absent....
POSTSCRIPTS
The faster the flow, the brighter the glow
Going with the flow is rarely a bad thing. Unless you’re talking about the notorious pathogen Pseudomonas. The bacterium is almost always surrounded by flowing water, and researchers are using part of that phenomenon to measure the flow of cells within the body. They discovered that the pathogen detects flow and changes its behavior accordingly by activating genes that the Princeton-based...
PRODUCTS
Cytometry System
The Aurora advanced-flow cytometry system from Cytek Biosciences Inc. is now available with five lasers, enabling users to see more than 30 colors from a single sample. The system provides ease of use, a high performance-to-price ratio, design flexibility in experiments, and high-quality data. Optical filters do not need to be changed, and use of any fluorochromes are excited by the onboard...
Cytek Biosciences Inc.
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Solar Cell Research Equipment
The Academic Research Line of solar cell printing, testing, and imaging equipment from infinityPV APS provides a framework for research within organic and Perovskite solar cells. The Research...
infinityPV ApS
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Nanoparticle Analyzer
The ZetaView QUATT nanoparticle analyzer from Analytik Ltd. features a multiwavelength video tracking microscope for the rapid analysis of size, concentration, fluorescence, electrophoretic mobility,...
Analytik Ltd.
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Portable Spectrometer Device
The GoSpectro device from GoyaLab transforms a smartphone or a tablet into a portable spectrometer. The device is compact, easy to use, connected, and affordable. It is sensitive over the...
GoyaLab
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2D Tube Rack Scanner
The DataPaq Mirage from Ziath Ltd. is a CMOS camera-based 2D tube rack scanner that can read Brooks Acoustix tubes in addition to all popular makes of coded tubes in ANSI/SLAS format racks. ...
Ziath Ltd.
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Objectives
X Line objectives from Olympus simultaneously boost numerical aperture, flatness, and chromatic correction, providing high image quality. A certain polishing technique produces ultra-thin...
Olympus Europa SE & Co. KG
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Image Analysis Software
Version 3.1 of the Vision4D image analysis software from arivis AG allows researchers to conduct analysis efforts supported by machine learning. The software’s machine learning...
Carl Zeiss Microscopy Software Center Rostock GmbH
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Pathological Laser System
The YC-200 Ophthalmic YAG Laser System and the YC-200 S plus Ophthalmic YAG and SLT Laser System from Nidek Co. Ltd. incorporate new optical design, engineering and software advances to ensure...
NIDEK CO. LTD.
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2D Imaging System Spectroradiometer
The VDU-1160-16 2D Imaging System Spectroradiometer from Gamma Scientific Inc. produces rapid and highly accurate display measurements including luminance, correlated color temperature, and CIE...
Gamma Scientific
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Wide Field-of-View Camera
A wide field of view (FOV) camera option for the Cytation 5 Cell Imaging Multi-Mode Reader has been announced by BioTek Instruments Inc. The camera captures approximately 4× the area...
BioTek Instruments Inc.
In-Vitro Smart Camera
JADAK’s Allegro In-Vitro Diagnostic 6-MP Smart Camera is a machine vision device designed specifically to complete standard pre-analytical tasks on a rack of vials. The camera accurately...
JADAK
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