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Microscopy Articles

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Superresolution Microscopy: An Imaging RevolutionSuperresolution Microscopy: An Imaging Revolution
Marie Freebody, Contributing Editor
Superresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...
Measuring Surface Roughness: The Benefits of Laser Confocal MicroscopyMeasuring Surface Roughness: The Benefits of Laser Confocal Microscopy
When evaluating the surface of a component, surface roughness can be assessed by eye or by rubbing it with a fingertip. Common expressions include “shiny,” “lusterless and...
Nanopositioning: A Step AheadNanopositioning: A Step Ahead
Scott Jordan, Brian Lula, and Stefan Vorndran, PI (Physik Instrumente) LP
By its original definition, a nanopositioning device is a mechanism capable of repeatedly delivering motion in increments as small as one nanometer. Lately demands from industry and research have...
Microscopy Illumination: Considering Nonlaser Light SourcesMicroscopy Illumination: Considering Nonlaser Light Sources
As recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...
Lasers for Microscopy: Major TrendsLasers for Microscopy: Major Trends
Marco Arrigoni, Nigel Gallaher, Darryl McCoy, Volker Pfeufer, Matthias Schulze, and Daniel Callen, Coherent Inc.
Laser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...
Interferometry: Measuring with LightInterferometry: Measuring with Light
Zygo Corporation
An interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...
NSOM: Discovering New WorldsNSOM: Discovering New Worlds
M. Kovar, Midako A. Nohe, N.O. Petersen and P.R. Norton, University of Western Ontario
NSOM is suitable for studies on the mesoscopic scale (several tens to hundreds of molecular dimensions). It has become an important tool in research and applications of semiconductors, organic layers...
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