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Biophotonics Monthly: Simplified Approach Makes Two-Photon Multicolor Imaging Less Costly (2/26/2014)

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Wednesday, February 26, 2014
Simplified Approach Makes Two-Photon Multicolor Imaging Less Costly
Simplified Approach Makes Two-Photon Multicolor Imaging Less Costly A method combining a fixed-wavelength laser with a nondescanned hyperspectral detection system renders clean images. Two-photon microscopy (TPM) is the method of choice for imaging biological samples in vivo, with cellular resolution in three dimensions. Multicolor imaging with several fluorophores – standard in single-photon microscopy – also is desirable in TPM, but existing approaches using multiple lasers are expensive.
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SERS on the Verge of Diagnostic Success
Applications poised to benefit from this emerging Raman technology include biology, forensics and pharmaceuticals. After years of exclusion as an academic technique, Raman spectroscopy has finally, firmly taken its place as an important analytical tool used for applications ranging from noninvasive imaging for diagnostics to in-field sensing for the detection of drugs and explosives.
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Raman Technique Offers Promise for Clinical Applications
Researchers have achieved some success in honing the sensitivity of this label-free technique for diagnostic applications. Raman imaging has been explored for a range of uses; among the most exciting of these are applications in the biomedical arena. Here, especially in the past decade or so, considerable attention has been paid to the potential of the technique for diagnosis of disease.
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Fast Camera Tracks Agile Survival Artists
Some like it hot – for example, micro-organisms that live in the deep sea on “black smokers,” where heat rises from the interior of the earth. These archaea, or “ur-bacteria,” form a separate branch in the phylogenetic tree of life and are veritable survival artists. Biologists have long wondered how exactly it is that archaea propel themselves.
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Laser Reveals Photosynthetic Processes
Scientists have used an ultrafast laser to study a photosynthetic complex — arguably the most important bit of organic chemistry on the planet — in its complete functioning state.
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Biophotonics Products
TOPTICA Photonics - iChrome MLE iChrome MLE
TOPTICA Photonics
Biophotonics instrumentation frequently requires several laser wavelengths from one package. TOPTICA´s exceptional iChrome MLE provides a perfect solution.
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Andor Technology plc - Multitrack Imaging Spectrograph Multitrack Imaging Spectrograph
Andor Technology plc
The Holospec multitrack imaging spectrograph by Andor Technology is suitable for various applications including weak nanostructure photoluminescence; micro-Raman mapping, including tip-enhanced Raman spectroscopy; spectrally assisted microfluidics; real-time medical diagnosis; standoff chemical detection; and online process control.
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Teledyne DALSA, Machine Vision OEM Components - CMOS X-Ray Detector CMOS X-Ray Detector
Teledyne DALSA, Machine Vision OEM Components
Teledyne Dalsa Inc. has added the Xineos-1515 CMOS x-ray detector to its flat detector series for clinical fixed and mobile applications such as C-arms, fluoroscopy and 3-D orthopedic imaging systems.
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Applied Scientific Instrumentation Inc. - Illumination Microscope Illumination Microscope
Applied Scientific Instrumentation Inc.
Applied Scientific Instrumentation (ASI) Inc.’s dual-inverted selective plane illumination microscope generates 3-D volumes with isotropic resolution (330 nm) in all directions.
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Industry Events
PITTCON 2014 - March 2 – 6 2014 · Chicago, IL
Visit Photonics Media at Booth 3844

PITTCON 2014 There are more than 2,000 technical sessions available to choose from with this year's conference at PITTCON. The 2014 comprehensive Technical Program will include, but not limited to, areas of analytical chemistry, applied spectroscopy, life sciences, bioanalysis, and food sciences.
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Photonics Buyers' Guide
Looking for Biophotonics products? Search the Photonics Buyers' Guide or Browse these product categories:

Gastroenterology Laser Systems
Mass Spectrometers
Microscope Cameras
Optical Coherence Tomography Imaging Systems
Photodynamic Therapy/Oncology Laser Systems
Tissue Welding Laser Systems
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