Sub-Cellular Biology at Tissue Scales with Cleared Tissue Axially Scanned Light-Sheet Microscopy
Wed, Aug 17, 2022 1:00 PM - 2:00 PM EDT
Large-scale interdisciplinary efforts have worked to comprehensively catalog cellular architectures in health and disease. Kevin Dean Ph.D. shares on the scalable imaging platform, Cleared-Tissue Axially Swept Light-Sheet Microscopy (CT-ASLM), that helps further this research. The CT-ASLM leverages high-speed, aberration-free, remote focusing to achieve an isotropic resolution of approximately 300 nm-scale subcellular imaging with an unparalleled optical sectioning capacity and large field of view. The platform provides global tissue architectures as well as quantitatively detailed morphological and biochemical descriptions of the individual cells that compose tissues in health and in disease. Sponsored by Power Technology.
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