Nov 2005Coherent Inc.Request Info
Laser Extends MPE Microscopy CapabilitiesSANTA CLARA, Calif., Nov. 8 -- Laser maker Coherent Inc.'s new Chameleon Ultra laser extends the capabilities of multiphoton excitation (MPE) microscopy by delivering an unmatched combination of wavelength tuning range, fast scanning and high peak power, according to the company. This new ultrafast laser tunes from 690 to 1040 nm, enabling calcium uncaging, autofluorescence techniques and the use of green, blue and cyan fluorescent proteins, as well as deeper imaging within samples. A fast scanning speed of 25 nm/s further supports calcium uncaging and facilitates multicolor imaging. The Chameleon Ultra also offers high peak power (>2 W at 800 nm) throughout its tuning range for a stronger MPE signal.
The Chameleon Ultra output has an M2 <1.1 and a round beam (ellipticity between 0.9 and 1.1) for optimum coupling with the microscope optical system. Chameleon Ultra also requires no manual adjustments, and is operated via a simple push-button, menu-driven interface on the power supply’s front panel. The laser can be controlled by a host computer using the supplied graphical user interface or, alternatively, the user can develop custom firmware based on the RS-232 command set or Labview VI.
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