Sep 2007Leica Microsystems GmbHRequest Info
A multicolor TIRF system that allows the entire fluorescence excitation spectrum to be used for real-time visualization of live-cell dynamics has been unveiled by Leica Microsystems GmbH. The AM TIRF MC integrates four solid-state lasers for the excitation of fluorophores at wavelengths from 405 to 632 nm. The system features switching times of 1 ms and an ultrahigh synchronized frame rate. The scanner sensor automatically matches the TIRF angle at all wavelengths to the required penetration depth.