Request InfoLeica Microsystems GmbHA multicolor TIRF system that allows the entire fluorescence excitation spectrum to be used for real-time visualization of live-cell dynamics has been unveiled by Leica Microsystems GmbH. The AM TIRF MC integrates four solid-state lasers for the excitation of fluorophores at wavelengths from 405 to 632 nm. The system features switching times of 1 ms and an ultrahigh synchronized frame rate. 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