Request InfoCoolLED Ltd.CoolLED has launched the pE-100, a fluorescence LED source. The device offers instant on/off and 0 to 100% intensity controls. It can be used on all microscopes with an external light source port for epifluorescent or transmitted light applications. Users can select their desired wavelength from more than 20 LED wavelengths. An optional cable is available for external transistor-transistor logic trigger. The instrument features quiet operation, fast switching, active cooling and no hazardous materials.See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Mar/Apr 2023 IssueLED Illumination SystemsThe pE-400 series of four-wavelength LED illumination systems from CoolLED provide sophisticated control and powerful illumination for cost-effective fluorescence microscopy. The series...Promoted Content April 2022 IssueKeyLight™ by Phoseon TechnologyKeyLight™ delivers intense, broad-spectrum UV and visible wavelengths for a wide variety of colors between 340 nm and 760 nm. These compact light sources support 3, 4, 5, 6 or 7 channel systems...Photonics.com 4/11/2024Machine Vision SpotlightThe Z-SPOT from TPL Vision is a high-power spotlight made for machine vision applications that require focused and directional illumination such as pick-and-place, assembly inspection, and barcode...Promoted Content November 2022 IssueLS850 Fully Automated MicroscopeThe powerful, new LS850 Microscope is the latest generation of our fully automated three-channel flagship model and offers the latest advances in optics, cameras, throughput, and user flexibility....ARTICLESPhotonics.com 2/23/2024SPAD Elevates Spatiotemporal Resolution in Conventional MicroscopesImage scanning microscopy (ISM), a superresolution technique enabled by the advent of fast and compact detector arrays, provides signal-to-noise ratio (SNR), optical sectioning, and spatial...Photonics.com 1/5/2024Targeted Spectroscopy Can Improve Treatment of Eye DiseaseA targeted spectroscopy system developed at Zilia Inc., by a team led by professor Dominic Sauvageau from the University of Alberta, enables concurrent imaging of the eye fundus — a region at...Photonics Spectra February 2024 IssueAlgorithm Boosts Live-Cell Imaging's CapabilitiesSuperresolution radial fluctuations (SRRF), a superresolution algorithm, works by observing fluctuations in radial symmetry throughout the frames of an image. SRRF supports live-cell, superresolution...BioPhotonics May/Jun 2023 IssueModule Uses Single-photon Microscopy to Track Cellular ActivityBrightEyes-TTM, an open-source time-tagging module (TTM) developed at the Italian Institute of Technology (IIT), enables scientists to observe the dynamic processes of molecules inside living cells...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookDetectors: Guideposts on the Road to SelectionAny number of medical, industrial, and analytical applications requires the detection of light. Chemiluminescence, bioluminescence, fluorescence, and atomic absorption are just a few, and all require...Photonics HandbookInterferometry: Measuring with LightAn interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...WHITEPAPERSPhotonics.com 1/10/2024Spectral, Spatial and Temporal Optimization of Solid-State Light Engine OutputSpecifications for illumination systems for biomedical imaging and industrial metrology generally converge on spectral, spatial and temporal light output characteristics. This article describes some...Photonics.com 1/10/2024Laser Light Engine Output StabilityIn this white paper, Dr. Iain Johnson, Lumencor’s Director of Technical Support, tests Lumencor’s laser-based CELESTA Light Engine for consistency, power, and stability using continuous wave...Photonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 2/28/2024Multi-Bandpass Filters for FluorescenceLearn how multi-bandpass filters combined with multiple LEDs can enable versatile and compact fluorescence instrumentation.WEBINARSPhotonics.com 6/2/2022Advances in LED Illumination for Fluorescence ImagingLED illumination for fluorescence microscopy systems has progressed significantly from a time when LED sources had low optical power and a limited range of wavelengths. While the benefits of LED...Photonics.com 1/13/2022LEDs: Expanding Capabilities for Live Cell ImagingThe light source of a widefield fluorescence microscope is often overlooked by scientists setting out to capture fast cellular processes with live cell imaging. But LEDs have changed the game. ...Photonics.com 9/22/2020LED Lighting for Fluorescence Microscopy: A Sustainable Illumination OptionFluorescence imaging in life sciences and microscopy applications has traditionally used mercury, metal halide, and xenon arc lamps for illumination. With advances in technology, LEDs are now able to...Photonics.com 1/10/2022Photonics Spectra Conference 2022: January 10 - 13Photonics Media will host its second annual Photonics Spectra Conference Jan. 10-13. The virtual event will comprise four technology tracks — Lasers, Optics, Sensors and Detectors, and Imaging...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionaryoptical filterAn optical filter is a device that selectively transmits or blocks specific wavelengths, or colors, of light. Optical filters are used to control the spectral content of light in various...Photonics DictionaryCMOS quantitative polymerase chain reaction systemThis type of miniaturized system, referred to as CMOS qPCR, combines microfluidic technology with an ultralow-light CMOS bio-optical sensor with LEDs as the optical excitation source to achieve...Photonics Dictionarysingle-photon avalanche diodeA single-photon avalanche diode (SPAD) is a specialized type of photodetector designed to detect extremely weak optical signals, down to the level of single photons. SPADs are widely used in...Photonics Dictionaryfluorescent screenA fluorescent screen refers to a phosphorescent or fluorescent-coated surface that emits visible light when exposed to other forms of electromagnetic radiation, such as x-rays or ultraviolet light....VIDEOSPhotonics.com 1/9/2024CELESTA Light Engine - Customer Success StorySolving MERFISH challenges for Spatial TranscriptomicsPhotonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 10/16/2013UV Disinfectant & Photon Chips - LIGHT MATTERS 10.16.2013-Photons on Demand -Spinning-disk Microscope -UV Disenfectant This week on Light matters: Photons on demand enable compact optical chips, a spinning-disk microscope peers deeply into a cell, and...Photonics.com 8/24/2022Ramacle® Software Highlight: Fast Mapping - Edinburgh InstrumentsThis Software Highlight focuses on Fast Mapping in our Ramacle software. Fast Mapping enables the user to acquire Raman maps with significantly reduced acquisition times via more efficient stage...PHOTONICS BUYERS' GUIDE CATEGORIESFluorescent Light SourcesA fluorescent light source is a tube containing mercury vapor and lined with a phosphor. When current is passed through the vapor the strong ultraviolet emission excites the phosphor, which emits...Fluorescence MicroscopesFluorescence SpectrometersFluorescence Imaging SystemsCOMPANIESPhotonics Buyers' GuideCoolLED Ltd.CoolLED designs and manufactures cutting edge LED illumination systems for researchers and clinicians using the latest LED technology. Since our team of four introduced the first commercially...Photonics Buyers' GuideAvantes BVAvantes has spent the last 30 years refining its mission as a trusted and innovative optical instruments and solutions source. Focused on applications and measurements, Avantes offers Spectrometers,...Photonics Buyers' GuideAvantier Inc.Avantier Inc. is an unparalleled leader in providing innovative imaging systems solutions and optical systems solutions. We offer advance precision custom optical design, optical engineering...Photonics Buyers' GuideEdinburgh Instruments Ltd.Founded in 1971, Edinburgh Instruments Ltd. is a global provider of sophisticated, state-of-the-art analytical instrumentation for optical spectroscopy. We design and manufacture a range of...