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Fiber Optic Immersion Probes
Apr 2010
Fibre Photonics Ltd.Request Info
LIVINGSTON, UK, April 22, 2010 — Fibre Photonics Ltd. has introduced clean-in-place (CIP) fiber optic attenuated total reflectance (ATR) immersion probes for use in immersion spectroscopy in the mid-infrared for pharmaceutical production.

Spectral range is from 0.18 to 18.0 µm (550 cm-1 to 55,500 cm-1). With automated CIP technology, cleaning is faster, less labor-intensive and more repeatable, and the risk of chemical exposure is reduced. Maintaining the integrity of optical analysis methods is critical in applications such as reaction monitoring, crystallization development and screening, process analytical technology, analytical characterization and biopharmaceutical analysis.

An optical system with automated CIP enables reliable analysis at any time during chemical and biological processes. The semi- or fully automated SensoGate-FOS (fiber optic spectroscope) and remotely operated Ceramat-FOS with the Unical-FOS 9000 controller are designed so that fiber optic immersion probes can be cleaned and used with ease. Monitoring of the cleaning process with a detector/analyzer is possible, and when the baseline is reached, drying starts and the probe is pushed back into the process measurement position.

The probes enable performance of real-time, in situ, reagent-free mid-infrared ATR spectroscopy during the development and production of fine chemicals, biopharmaceuticals, and food and drink products.

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