Request InfoBeckman Coulter Inc., Diagnostics Div.Beckman Coulter Inc. has introduced Krome Orange, a violet-excited organic dye that expands the range of choices and dye sensitivity limits for violet lasers. Common gating markers can be transferred to this fluorochrome, freeing other channels for use with more esoteric markers and enabling more versatile 10-color flow cytometry applications. It has excitation and emission maxima of 398 and 528 nm, respectively, and provides a brighter signal than Pacific Orange conjugates with equivalent spectral overlaps into adjacent channels. The dye enables scientists to increase sensitivity for low...See full productRelated content from Photonics MediaPRODUCTSPhotonics.com 2/15/2024Bandpass Optical FiltersThe Semrock Nanopede™ Optical Filters from IDEX Health & Science cover the near UV and visible spectrum 20 nm full-width, half-max steps. Developed for applications in spectral flow...Photonics Spectra April 2024 IssueReagent Cocktail Preparation SystemThe Cytek Orion™ from Cytek Biosciences is an automated reagent cocktail preparation system for flow cytometry that eliminates the need for technicians to manually prepare multicolor antibody...Promoted Content December 2023 IssueLife Science Product DevelopmentOptikos engineering services will help bring your next life sciences product from design to market. Our team of Optical Engineering Experts® has proven success in handling the optical roadblocks...Promoted Content May 2023 IssueLasers and Component SpectrometersMetrohm has opened a new webshop for lasers, component spectrometers, and Raman spectroscopy sampling solutions. The new m-oem brand includes four Metrohm companies: Innovative Photonic Solutions...ARTICLESPhotonics.com 9/19/2022Cascaded Neural Networks Help Virtually Re-Stain Tissue SamplesUsing a cascaded deep neural network structure, a UCLA research group led by professor Aydogan Ozcan developed a computational approach for chemical-free re-staining of tissue specimens. The...BioPhotonics Jan/Feb 2024 IssueVirtual Histology: Democratizing Diagnostic Anatomic PathologyA virtually stained kidney tissue image showing compact nests and sheets of cells with clear cytoplasm and distinct membrane. Courtesy of the Ozcan Lab/UCLA. Histology is the microscopic...BioPhotonics Sep/Oct 2023 IssueIllumination Advancing Fluorescence Microscopy in Life Sciences, Medical RealmsIn many academic research and medical settings, microscopy and imaging have transitioned from using traditional lamp illumination, such as mercury and Xenon lamphouses, to solid-state LED...BioPhotonics.com December 2023 IssueFlow Cytometry Uncovers Predictive Biomarker for Severe COVIDUsing image-based flow cytometry, researchers at the Technical University of Munich (TUM) identified a biomarker for predicting how serious a COVID-19 infection will be. They also developed a rapid...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookLasers: Understanding the BasicsOver 60 years have passed since the first demonstration of a laser in 1960. After the initial spark of interest, lasers were for a while categorized as “a solution waiting for a problem,”...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...WHITEPAPERSPhotonics.com 2/16/2024PZ-2000 FT Series Automated Stage with Piezo Z-Axis Top PlateOverview of PZ-2000 FT.Photonics.com 9/27/2023Raman SpectroscopyTo achieve accurate and precise Raman measurements, optical filters play a crucial role in enhancing signal-to-noise ratio, and reducing background interference. This white paper explores the...Photonics.com 12/8/2022Sub 50 Femtosecond Pulse Lasers for Gentler Multiphoton MicroscopyFinding the ideal ultra-fast laser source for a multiphoton imaging setup is not trivial. It is a fine balance between peak power, pulse energy and laser wavelength. In this white paper we show that...Photonics.com 1/10/2024Single-Objective Light SheetAn overview of the Single-Objective Light Sheet.WEBINARSPhotonics.com 6/11/2015Biophotonic Imaging for Medicine: A Digital ConferenceResearchers from around the world presented their latest work at “Biophotonic Imaging for Medicine: A Digital Conference.” Presentations focused on a range of light-based imaging and...Photonics.com 6/2/2022Advances in LED Illumination for Fluorescence ImagingLED illumination for fluorescence microscopy systems has progressed significantly from a time when LED sources had low optical power and a limited range of wavelengths. While the benefits of LED...Photonics.com 1/16/2018The MUSE Microscope for Advancing Light MicroscopyThis webinar will introduce the MUSE (Microscopy with Ultraviolet Surface Excitation) Microscope, a novel form of light microscopy that can generate high-quality histology and histopathology images...Photonics.com 5/19/2020Squeezing More Out of Light: Innovative Approaches to Time-Resolved Flow CytometryIn this webinar, presenter Giacomo Vacca, Ph.D., founder and president of Kinetic River, will discuss recent advances in time-resolved methods of flow cytometry and how these advances are being...PHOTONICS DICTIONARY+ TERMSPhotonics DictionaryfluorophoreA fluorophore is a molecule or a portion of a molecule that has the ability to emit light upon excitation by an external energy source, such as ultraviolet or visible light. The process by which a...Photonics DictionaryfluorescenceFluorescence is a type of luminescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. Specifically, fluorescence involves the absorption of...Photonics Dictionaryfluorescence microscopyFluorescence microscopy is a specialized optical imaging technique used in biology, chemistry, and materials science to visualize and study specimens that exhibit fluorescence. Fluorescence is the...Photonics Dictionaryflow cytometryFlow cytometry is a powerful technique used in biology and medicine for the quantitative analysis of the physical and chemical characteristics of cells and particles suspended in a fluid. The method...VIDEOSPhotonics.com 1/9/2024VOLTA Scanner: An Optical High-Throughput Plate Reader for Transmembrane Ion-Channel AnalysesSay goodbye to the limitations of manual patch clamp and outdated electrophysiological investigations. With the emergence of automated patch clamping (APC) nearly two decades ago, higher throughput...Photonics.com 7/9/2013Continuum - Introducing Vista, Peak Performance Dye LaserThe Vista dye laser offers the highest resolution (30%) and the finest precision scanning, all combined to deliver optimal performance with every scan. Continuum (408) 727-3240 www.continuumlasers.comPhotonics.com 4/19/2022Optolong Fluorescence Filter Set Comparation FITC/DAPI/TexasRed - Optolong Optics Co. Ltd.Fluorescent filter is a key component of biomedical and life science instruments, and its main function is to separate and select the characteristic band spectra of excitation light and emission...Photonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...PHOTONICS BUYERS' GUIDE CATEGORIESLaser Pumped Dye LasersAbsorbing DyesFluorescent DyesLaser DyesA laser dye is a class of organic dyes that emit coherent radiation over a wide spectral range.COMPANIESPhotonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideOptikos CorporationThe Optical Engineering Experts® Optikos designs and manufactures metrology products for measuring and assuring optical image quality; and provides optical engineering design, development,...Photonics Buyers' GuideCASTECH INC.CASTECH is a recognized leading supplier of nonlinear optical crystals, laser crystals and precision optical components for laser, telecom, medical, analysis and detector markets. Products...Photonics Buyers' GuideFresnel Technologies Inc.Fresnel Technologies Inc. is an expert manufacturer of molded plastic optics, including Fresnel lenses and related optical components, as well as infrared transmitting materials and optics made from...